Therapeutic exploitation of IPSE, a urogenital parasite‐derived host modulatory protein, for chemotherapy‐induced hemorrhagic cystitis

Chemotherapy‐induced hemorrhagic cystitis (CHC) can be difficult to manage. Prior work suggests that IL‐4 alleviates ifosfamide‐induced hemorrhagic cystitis (IHC), but systemically administered IL‐4 causes significant side effects. We hypothesized that the Schistosoma hematobium homolog of IL‐4‐indu...

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Veröffentlicht in:	The FASEB journal 2018-08, Vol.32 (8), p.4408-4419
Hauptverfasser:	Mbanefo, Evaristus C., Le, Loc, Pennington, Luke F., Odegaard, Justin I., Jardetzky, Theodore S., Alouffi, Abdulaziz, Falcone, Franco H., Hsieh, Michael H.
Format:	Artikel
Sprache:	eng
Schlagworte:	anti‐inflammatory ifosfamide infiltrin Schistosoma urothelial
Online-Zugang:	Volltext
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