A Vascular-appearing Spindle Cell Xanthogranuloma in a Child
Spindle cell xanthogranuloma is a rare variant of juvenile xanthogranuloma that most commonly presents in adults as papulonodules. We describe a vascular-appearing case of spindle cell xanthogranuloma on the nose of a 10-year-old boy. The lesion was a dark red, well-demarcated, dome-shaped papule. H...
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Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2018-05, Vol.10 (5), p.e2595 |
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description | Spindle cell xanthogranuloma is a rare variant of juvenile xanthogranuloma that most commonly presents in adults as papulonodules. We describe a vascular-appearing case of spindle cell xanthogranuloma on the nose of a 10-year-old boy. The lesion was a dark red, well-demarcated, dome-shaped papule. Histopathology revealed spindle-shaped histiocytes in a storiform pattern that stained positive for cluster of differentiation 68 (CD68) and the nuclear antigen Ki-67. No vascular features were found. To our knowledge, this is the first reported spindle cell xanthogranuloma to mimic an angiomatous lesion. |
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We describe a vascular-appearing case of spindle cell xanthogranuloma on the nose of a 10-year-old boy. The lesion was a dark red, well-demarcated, dome-shaped papule. Histopathology revealed spindle-shaped histiocytes in a storiform pattern that stained positive for cluster of differentiation 68 (CD68) and the nuclear antigen Ki-67. No vascular features were found. To our knowledge, this is the first reported spindle cell xanthogranuloma to mimic an angiomatous lesion.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.2595</identifier><identifier>PMID: 30009107</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Case reports ; Dermatology ; Histopathology ; Literature reviews ; Pediatrics ; Tumors</subject><ispartof>Curēus (Palo Alto, CA), 2018-05, Vol.10 (5), p.e2595</ispartof><rights>Copyright © 2018, Morse et al. 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subjects | Case reports Dermatology Histopathology Literature reviews Pediatrics Tumors |
title | A Vascular-appearing Spindle Cell Xanthogranuloma in a Child |
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