Efficient production of human interferon beta in the white of eggs from ovalbumin gene–targeted hens

Transgenic chickens could potentially serve as bioreactors for commercial production of recombinant proteins in egg white. Many transgenic chickens have been generated by randomly integrating viral vectors into their genomes, but transgene expression has proved insufficient and/or limited to the ini...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Scientific reports 2018-07, Vol.8 (1), p.10203-12, Article 10203
Hauptverfasser:	Oishi, Isao, Yoshii, Kyoko, Miyahara, Daichi, Tagami, Takahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	42/41 631/61/17/1511 631/61/185 82/51 82/80 96/21 Albumen Animals Animals, Genetically Modified Biological activity Bioreactors Chickens Chickens - genetics CRISPR Egg White - chemistry Eggs Embryonic Germ Cells - cytology Embryonic Germ Cells - metabolism Embryos Expression vectors Feasibility Studies Female Gene Knock-In Techniques Genetic Loci Genomes Germ cells Humanities and Social Sciences Humans Industrial applications Insertion Interferon-beta - genetics Interferon-beta - metabolism multidisciplinary Offspring Ovalbumin Ovalbumin - genetics Poultry Science Science (multidisciplinary) Transplantation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!