An experimental investigation of a novel iron chelating protoporphyrin IX prodrug for the enhancement of photodynamic therapy

Objectives Non‐melanoma skin cancers are the most frequently occurring type of cancer worldwide. They can be effectively treated using topical dermatological photodynamic therapy (PDT) employing protoporphyrin IX (PpIX) as the active photosensitising agent as long as the disease remains superficial....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Lasers in surgery and medicine 2018-07, Vol.50 (5), p.552-565
Hauptverfasser:	Anayo, Lizette, Magnussen, Anette, Perry, Alexis, Wood, Mark, Curnow, Alison
Format:	Artikel
Sprache:	eng
Schlagworte:	Accumulation Adjuvants aminolaevulinic acid (ALA) AP2‐18 Basic Science Cancer Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - therapy Cell activation Cell Culture Techniques Chelating agents Chelation CP94 dermatology Epithelial Cells - drug effects Epithelial Cells - pathology Fibroblasts Fibroblasts - drug effects Fibroblasts - pathology Fluorescence Humans Iron Iron chelating agents Iron Chelating Agents - pharmacology iron chelation Iron constituents Irradiation L-Lactate dehydrogenase Lactate dehydrogenase Lactic acid Lasers Lungs Melanoma methyl‐aminolevulinate (MAL) Photochemotherapy Photodynamic therapy photodynamic therapy (PDT) Photosensitization Photosensitizing Agents - pharmacology Precursors Prodrugs Protoporphyrin Protoporphyrin IX protoporphyrin IX (PpIX) Protoporphyrins pyridinone Pyridones - pharmacology Radiation Reagents skin Skin cancer Skin Neoplasms - pathology Skin Neoplasms - therapy Supplements Surgery
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!