Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling

X-linked inhibitor of apoptosis (XIAP) plays an important role in preventing apoptotic cell death. XIAP has been shown to participate in signaling pathways, including Wnt signaling. XIAP regulates Wnt signaling by promoting the monoubiquitylation of the co-repressor Groucho/TLE family proteins, decr...

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Veröffentlicht in:	Journal of cell science 2018-05, Vol.131 (10), p.jcs210575-jcs210575
Hauptverfasser:	Ng, Victoria H, Hang, Brian I, Sawyer, Leah M, Neitzel, Leif R, Crispi, Emily E, Rose, Kristie L, Popay, Tessa M, Zhong, Alison, Lee, Laura A, Tansey, William P, Huppert, Stacey, Lee, Ethan
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Apoptosis Cell death DIABLO protein Drug development Embryos Heparan sulfate LEF protein Phosphorylation Proteins Short Report Signaling Threonine Transcription factors Wnt protein XIAP protein β-catenin
Online-Zugang:	Volltext
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