Glucocorticoid Signaling Enhances Expression of Glucose-Sensing Molecules in Immature Pancreatic Beta-Like Cells Derived from Murine Embryonic Stem Cells In Vitro

Pluripotent stem cells may serve as an alternative source of beta-like cells for replacement therapy of type 1 diabetes; however, the beta-like cells generated in many differentiation protocols are immature. The maturation of endogenous beta cells involves an increase in insulin expression starting...

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Veröffentlicht in:	Stem cells and development 2018-07, Vol.27 (13), p.898-909
Hauptverfasser:	Ghazalli, Nadiah, Wu, Xiaoxing, Walker, Stephanie, Trieu, Nancy, Hsin, Li-Yu, Choe, Justin, Chen, Chialin, Hsu, Jasper, LeBon, Jeanne, Kozlowski, Mark T., Rawson, Jeffrey, Tirrell, David A., Yip, M.L. Richard, Ku, Hsun Teresa
Format:	Artikel
Sprache:	eng
Schlagworte:	Original Research Reports
Online-Zugang:	Volltext
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