Comparison of Genotypic and Phenotypic Correlations: Cheverud's Conjecture in Humans

Accurate estimation of genetic correlation requires large sample sizes and access to genetically informative data, which are not always available. Accordingly, phenotypic correlations are often assumed to reflect genotypic correlations in evolutionary biology. Cheverud's conjecture asserts that...

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Veröffentlicht in:	Genetics (Austin) 2018-07, Vol.209 (3), p.941-948
Hauptverfasser:	Sodini, Sebastian M, Kemper, Kathryn E, Wray, Naomi R, Trzaskowski, Maciej
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal species Anthropology Bioinformatics Biological Evolution Biological Specimen Banks Correlation analysis Datasets Empirical analysis Estimates European Continental Ancestry Group - genetics Evolution Evolutionary biology Genetic Variation Genetics Genetics, Population Genome-Wide Association Study - methods Genomes Genotype Heritability Human populations Humans Independent sample Investigations Linkage Disequilibrium Morphology Phenotype Populations Quantitative genetics Quantitative Trait Loci Regression analysis Sample size Statistical analysis Statistical methods United Kingdom
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