Recent alcohol use prolongs hospital length of stay following lung transplant

Little is known about the alcohol habits of people with advanced lung disease. Following lung transplantation, patients are asked to abstain from or minimize alcohol use. The aim of this investigation was to assess alcohol use in a cohort of patients with advanced lung disease undergoing evaluation...

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Veröffentlicht in:Clinical transplantation 2018-06, Vol.32 (6), p.e13250-n/a
Hauptverfasser: Lowery, Erin M., Yong, Meagan, Cohen, Arala, Joyce, Cara, Kovacs, Elizabeth J.
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container_issue 6
container_start_page e13250
container_title Clinical transplantation
container_volume 32
creator Lowery, Erin M.
Yong, Meagan
Cohen, Arala
Joyce, Cara
Kovacs, Elizabeth J.
description Little is known about the alcohol habits of people with advanced lung disease. Following lung transplantation, patients are asked to abstain from or minimize alcohol use. The aim of this investigation was to assess alcohol use in a cohort of patients with advanced lung disease undergoing evaluation for lung transplant. This is a prospective observational investigation comparing patient self‐report of alcohol use with their responses on the Alcohol Use Disorders Identification Test (AUDIT), and alcohol biomarkers collected at the time of transplant. There were 86 included in the cohort, 34% currently using alcohol, 13% had AUDIT scores >3, and 10% had positive results for alcohol biomarkers at the time of transplantation. Patients with evidence of recent alcohol use prior to lung transplant surgery had a 1.5‐fold increase in hospital length of stay following lung transplant (P = .028), spent 3 times as long on mechanical ventilation after transplant, and required intensive care unit monitoring nearly 3 times longer than those without recent alcohol use (P = .008). There were no differences in primary graft dysfunction, although several patients with recent alcohol use had post‐transplant atrial arrhythmias, acute kidney injury, and acute cellular rejection. Abstaining from alcohol use may optimize outcomes following lung transplant.
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Patients with evidence of recent alcohol use prior to lung transplant surgery had a 1.5‐fold increase in hospital length of stay following lung transplant (P = .028), spent 3 times as long on mechanical ventilation after transplant, and required intensive care unit monitoring nearly 3 times longer than those without recent alcohol use (P = .008). There were no differences in primary graft dysfunction, although several patients with recent alcohol use had post‐transplant atrial arrhythmias, acute kidney injury, and acute cellular rejection. 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Patients with evidence of recent alcohol use prior to lung transplant surgery had a 1.5‐fold increase in hospital length of stay following lung transplant (P = .028), spent 3 times as long on mechanical ventilation after transplant, and required intensive care unit monitoring nearly 3 times longer than those without recent alcohol use (P = .008). There were no differences in primary graft dysfunction, although several patients with recent alcohol use had post‐transplant atrial arrhythmias, acute kidney injury, and acute cellular rejection. 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source MEDLINE; Access via Wiley Online Library
subjects advanced lung disease
Aged
alcohol
Alcohol Drinking - trends
Female
Follow-Up Studies
Humans
Length of Stay - statistics & numerical data
Lung Diseases - surgery
lung transplant
Lung Transplantation - methods
Male
Middle Aged
Postoperative Complications
Prognosis
Prospective Studies
Risk Factors
title Recent alcohol use prolongs hospital length of stay following lung transplant
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