MARSI: metabolite analogues for rational strain improvement

Abstract Summary Metabolite analogues (MAs) mimic the structure of native metabolites, can competitively inhibit their utilization in enzymatic reactions, and are commonly used as selection tools for isolating desirable mutants of industrial microorganisms. Genome-scale metabolic models representing...

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Veröffentlicht in:	Bioinformatics 2018-07, Vol.34 (13), p.2319-2321
Hauptverfasser:	Cardoso, João G R, Zeidan, Ahmad A, Jensen, Kristian, Sonnenschein, Nikolaus, Neves, Ana Rute, Herrgård, Markus J
Format:	Artikel
Sprache:	eng
Schlagworte:	Applications Notes bioinformatics chemical reactions culture media drugs enzymatic reactions genes metabolites microorganisms mutants phenotype recombinant DNA
Online-Zugang:	Volltext
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