The 1.19 A X-ray structure of 2'-O-Me(CGCGCG)2 duplex shows dehydrated RNA with 2-methyl-2,4-pentanediol in the minor groove
The crystal and molecular structure of 2'-O-Me(CGCGCG)2 has been determined at 1.19 A resolution, at 100 K, using synchrotron radiation. The structure in space group P3212 is a half-turn right-handed helix that includes two 2-methyl-2,4-pentanediol (MPD) molecules bound in the minor groove. The...
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| Veröffentlicht in: | Nucleic acids research 2001-10, Vol.29 (20), p.4144-4153 |
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| Format: | Artikel |
| Sprache: | eng |
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