FOXP3 and miR-155 cooperate to control the invasive potential of human breast cancer cells by down regulating ZEB2 independently of ZEB1

Control of oncogenes, including ZEB1 and ZEB2, is a major checkpoint for preventing cancer, and loss of this control contributes to many cancers, including breast cancer. Thus tumour suppressors, such as FOXP3, which is mutated or lost in many cancer tissues, play an important role in maintaining no...

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Veröffentlicht in:Oncotarget 2018-06, Vol.9 (45), p.27708-27727
Hauptverfasser: Brown, Cheryl Y, Dayan, Sonia, Wong, Soon Wei, Kaczmarek, Adrian, Hope, Christopher M, Pederson, Stephen M, Arnet, Victoria, Goodall, Gregory J, Russell, Darryl, Sadlon, Timothy J, Barry, Simon C
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Sprache:eng
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