Activation of Sonic Hedgehog Signaling Is Associated with Human Osteosarcoma Cells Radioresistance Characterized by Increased Proliferation, Migration, and Invasion

BACKGROUND Radioresistance restricts the application of radiotherapy in human osteosarcoma (OS). This study investigated the molecular mechanism of radioresistance in OS, which may provide clues to finding ideal targets for genetic therapy. MATERIAL AND METHODS The human OS cell line MG63 was employ...

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Veröffentlicht in:	Medical science monitor 2018-06, Vol.24, p.3764-3771
Hauptverfasser:	Qu, Wei, Li, Dichen, Wang, Yufei, Wu, Qining, Hao, Dingjun
Format:	Artikel
Sprache:	eng
Schlagworte:	Lab/In Vitro Research
Online-Zugang:	Volltext
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