Chlamydia muridarum Genital and Gastrointestinal Infection Tropism Is Mediated by Distinct Chromosomal Factors

Some members of the genus , including the human pathogen , infect multiple tissues, including the genital and gastrointestinal (GI) tracts. However, it is unknown if bacterial targeting to these sites is mediated by multifunctional or distinct chlamydial factors. We previously showed that disruption...

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Veröffentlicht in:	Infection and immunity 2018-07, Vol.86 (7)
Hauptverfasser:	Morrison, Sandra G, Giebel, Amanda M, Toh, Evelyn C, Spencer, 3rd, Horace J, Nelson, David E, Morrison, Richard P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chlamydia Infections - etiology Chlamydia Infections - immunology Chlamydia muridarum - pathogenicity Chromosomes - physiology Codon, Nonsense Cytotoxins - genetics Female Gastrointestinal Diseases - etiology Gastrointestinal Diseases - immunology Gastrointestinal Tract - microbiology Genitalia - microbiology HeLa Cells Humans Mice Mice, Inbred C57BL Molecular Pathogenesis Organ Specificity Polymorphism, Single Nucleotide Reproductive Tract Infections - etiology Reproductive Tract Infections - immunology Tropism
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