NFM-10. TARGETING NuRD AND KAT7 FOR EPIGENOME MODIFICATION IN NEUROFIBROMATOSIS1 ASSOCIATED MALIGNANT PERIPHERAL NERVE SHEATH TUMORS

Abstract Neurofibromatosis type 1 (NF1) is common, occurring in 1/3000 live births, and results in skin pigmentation and the growth of tumors along nerves in the skin, brain, and other parts of the body. Loss of polycomb repressive complex 2 (PRC2) has been implicated in the tumorigenesis of Schwann...

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Veröffentlicht in:	Neuro-oncology (Charlottesville, Va.) Va.), 2018-06, Vol.20 (suppl_2), p.i144-i144
Hauptverfasser:	Mayanil, Chandra, Khan, Mariam, Mohanty, Vineet, Kumar, Raj, Xi, Guifa, Ichi, Shunsuke, Singh, Bal Ram, Mania-Farnell, Barbara, Tomita, Tadanori
Format:	Artikel
Sprache:	eng
Schlagworte:	Abstracts
Online-Zugang:	Volltext
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