Programmed death‐ligand 1 expression in gastric cancer: correlation with mismatch repair deficiency and HER2‐negative status

Gastric cancer (GC) is one of the most common malignancies. Immunotherapy is a promising targeted treatment. The immune regulatory programmed death‐1 (PD‐1)/programmed death‐ligand 1 (PD‐L1) axis has been used as a checkpoint target for immunotherapy. Currently, considerable discrepancies exist conc...

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Veröffentlicht in:	Cancer medicine (Malden, MA) MA), 2018-06, Vol.7 (6), p.2612-2620
Hauptverfasser:	Wang, Lei, Zhang, Qiongyan, Ni, Shujuan, Tan, Cong, Cai, Xu, Huang, Dan, Sheng, Weiqi
Format:	Artikel
Sprache:	eng
Schlagworte:	B7-H1 Antigen - genetics B7-H1 Antigen - metabolism Biomarkers, Tumor Cancer Biology Cell Line, Tumor DNA Mismatch Repair Female Gastric cancer Gene Expression Regulation, Neoplastic HER2 Humans Immunohistochemistry Kaplan-Meier Estimate Male mismatch repair deficiency Neoplasm Grading Neoplasm Staging Original Research Prognosis programmed death‐ligand 1 Receptor, ErbB-2 - genetics Receptor, ErbB-2 - metabolism Stomach Neoplasms - genetics Stomach Neoplasms - metabolism Stomach Neoplasms - pathology
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