Relationship Between T-Cell Responses to CMV, Markers of Inflammation, and Frailty in HIV-uninfected and HIV-infected Men in the Multicenter AIDS Cohort Study

The magnitude of CD4 and CD8 T-cell responses to CMV antigens correlated strongly with markers of immune activation, and significantly predicted onset of frailty in nonfrail HIV-uninfected men. These responses may influence immune activation in people with chronic CMV infection. Abstract Background...

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Veröffentlicht in:The Journal of infectious diseases 2018-06, Vol.218 (2), p.249-258
Hauptverfasser: Margolick, Joseph B, Bream, Jay H, Nilles, Tricia L, Li, Huifen, Langan, Susan J, Deng, Shane, Wang, Ruibin, Wada, Nikolas, Leng, Sean X
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Sprache:eng
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