Comparative evaluation of remineralization potential of casein phosphopeptide- amorphous calcium fluoride phosphate and novamin on artificially demineralized human enamel: An In vitro study
Aim: This study aimed to quantitatively compare the remineralization potential of casein phosphopeptide-amorphous calcium fluoride phosphate (CPP-ACFP) and Novamin on artificially induced enamel subsurface lesions using scanning electron microscope-energy dispersive X-ray (SEM-EDX). Materials and Me...
Gespeichert in:
| Veröffentlicht in: | Contemporary clinical dentistry 2018-06, Vol.9 (5), p.58-63 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 63 |
|---|---|
| container_issue | 5 |
| container_start_page | 58 |
| container_title | Contemporary clinical dentistry |
| container_volume | 9 |
| creator | Manoharan, Vidya Kumar, R Sivanraj, Arun Arumugam, Selva |
| description | Aim: This study aimed to quantitatively compare the remineralization potential of casein phosphopeptide-amorphous calcium fluoride phosphate (CPP-ACFP) and Novamin on artificially induced enamel subsurface lesions using scanning electron microscope-energy dispersive X-ray (SEM-EDX). Materials and Methods: Enamel specimens were prepared from seventy caries-free premolars and were kept for demineralization for 4 days. Following demineralization, enamel specimens were assigned to three groups: (1) Control group, (2) Group with CPP-ACFP-containing toothpaste, and (3) Group with Novamin-containing toothpaste. Further, both the experimental groups (CPP-ACFP group and Novamin) were then divided into three subgroups based on the duration of re-mineralization as follows: (a) 7 days, (b) 14 days, and (c) 21 days. Enamel specimens of experimental groups were then subjected to SEM-EDX to evaluate mineral content after treating with CPP-ACFP and Novamin. Results: Both the experimental groups showed very high significant differences between Ca/P ratios of remineralized samples. Conclusion: Even though both CPP-ACFP and Novamin showed remineralization potential, remineralization was found to be higher in the samples treated with CPP-ACFP. |
| doi_str_mv | 10.4103/ccd.ccd_28_18 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6006878</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A542196662</galeid><sourcerecordid>A542196662</sourcerecordid><originalsourceid>FETCH-LOGICAL-c568t-75d672d745fb15cbd420e1fa2c4a827f163bad9745f1b1dae70dcc195096439b3</originalsourceid><addsrcrecordid>eNptkl9r2zAUxc3YWEvXx70OwWDsxZkk27K9h0EI-1Mo7GWDvQlZum7UypInyQnZd9t3m0zStBm1EZbv_enIPjpZ9prgRUlw8UFKtUiD04aT5ll2jtua5bRg5PlxXv86yy5DuMXpKtoSV-XL7Iy2LaM1q86zvys3jMKLqDeAYCPMlKbOItcjD4O24IXRf_a10UWwUQszd6UIoFNt7UIaI4xRK8iRGJxP71NIgJF6GlBvJudT74CKCEhYhazbiKSPkq7wUfdaJmGzQ-phV1BoPQ3CIrBiAPMRLS26smijo3coxEntXmUvemECXB6eF9nPL59_rL7l19-_Xq2W17msWBPzulKspqouq74jlexUSTGQXlBZiobWPWFFJ1Q790lHlIAaKylJW-GWlUXbFRfZp73uOHUDKJlsSF_IR68H4XfcCc1PO1av-Y3bcIYxa-omCbw_CHj3e4IQ-aCDBGOEhWQWp5gVNSEFpQl9-x966yZv0-8lqkoEKfAj6kYY4Nr2Lu0rZ1G-rEpKWsbYTC2eoNI9uyydhV6n-smCd48WrEGYuA7OTPP5h1Mw34PSuxA89EczCOZzNvmcy2M2E__msYNH-j6JDxZvnYngw52ZtuB5Yu-s2z6tyquG3-e3-AcMbfs-</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2053221302</pqid></control><display><type>article</type><title>Comparative evaluation of remineralization potential of casein phosphopeptide- amorphous calcium fluoride phosphate and novamin on artificially demineralized human enamel: An In vitro study</title><source>Medknow Open Access Medical Journals</source><source>DOAJ Directory of Open Access Journals</source><source>PubMed Central Open Access</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Manoharan, Vidya ; Kumar, R ; Sivanraj, Arun ; Arumugam, Selva</creator><creatorcontrib>Manoharan, Vidya ; Kumar, R ; Sivanraj, Arun ; Arumugam, Selva</creatorcontrib><description>Aim: This study aimed to quantitatively compare the remineralization potential of casein phosphopeptide-amorphous calcium fluoride phosphate (CPP-ACFP) and Novamin on artificially induced enamel subsurface lesions using scanning electron microscope-energy dispersive X-ray (SEM-EDX). Materials and Methods: Enamel specimens were prepared from seventy caries-free premolars and were kept for demineralization for 4 days. Following demineralization, enamel specimens were assigned to three groups: (1) Control group, (2) Group with CPP-ACFP-containing toothpaste, and (3) Group with Novamin-containing toothpaste. Further, both the experimental groups (CPP-ACFP group and Novamin) were then divided into three subgroups based on the duration of re-mineralization as follows: (a) 7 days, (b) 14 days, and (c) 21 days. Enamel specimens of experimental groups were then subjected to SEM-EDX to evaluate mineral content after treating with CPP-ACFP and Novamin. Results: Both the experimental groups showed very high significant differences between Ca/P ratios of remineralized samples. Conclusion: Even though both CPP-ACFP and Novamin showed remineralization potential, remineralization was found to be higher in the samples treated with CPP-ACFP.</description><identifier>ISSN: 0976-237X</identifier><identifier>EISSN: 0976-2361</identifier><identifier>DOI: 10.4103/ccd.ccd_28_18</identifier><identifier>PMID: 29962765</identifier><language>eng</language><publisher>India: Wolters Kluwer India Pvt. Ltd</publisher><subject>Acids ; Calcification ; Calcium phosphates ; Casein ; Chloride ; Comparative analysis ; Demineralization ; Dental caries ; Dental enamel ; Dental research ; Dentistry ; Enamel ; Enamel and enameling ; Fluorides ; Fluorspar ; Mineralization ; Original ; Orthodontics ; Physiological aspects ; Premolars ; Public health ; Remineralization ; Scanning electron microscopy ; Sodium ; Statistical analysis</subject><ispartof>Contemporary clinical dentistry, 2018-06, Vol.9 (5), p.58-63</ispartof><rights>COPYRIGHT 2018 Medknow Publications and Media Pvt. Ltd.</rights><rights>Copyright Medknow Publications & Media Pvt. Ltd. Jun 2018</rights><rights>Copyright: © 2018 Contemporary Clinical Dentistry 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c568t-75d672d745fb15cbd420e1fa2c4a827f163bad9745f1b1dae70dcc195096439b3</citedby><cites>FETCH-LOGICAL-c568t-75d672d745fb15cbd420e1fa2c4a827f163bad9745f1b1dae70dcc195096439b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006878/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006878/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27457,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29962765$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Manoharan, Vidya</creatorcontrib><creatorcontrib>Kumar, R</creatorcontrib><creatorcontrib>Sivanraj, Arun</creatorcontrib><creatorcontrib>Arumugam, Selva</creatorcontrib><title>Comparative evaluation of remineralization potential of casein phosphopeptide- amorphous calcium fluoride phosphate and novamin on artificially demineralized human enamel: An In vitro study</title><title>Contemporary clinical dentistry</title><addtitle>Contemp Clin Dent</addtitle><description>Aim: This study aimed to quantitatively compare the remineralization potential of casein phosphopeptide-amorphous calcium fluoride phosphate (CPP-ACFP) and Novamin on artificially induced enamel subsurface lesions using scanning electron microscope-energy dispersive X-ray (SEM-EDX). Materials and Methods: Enamel specimens were prepared from seventy caries-free premolars and were kept for demineralization for 4 days. Following demineralization, enamel specimens were assigned to three groups: (1) Control group, (2) Group with CPP-ACFP-containing toothpaste, and (3) Group with Novamin-containing toothpaste. Further, both the experimental groups (CPP-ACFP group and Novamin) were then divided into three subgroups based on the duration of re-mineralization as follows: (a) 7 days, (b) 14 days, and (c) 21 days. Enamel specimens of experimental groups were then subjected to SEM-EDX to evaluate mineral content after treating with CPP-ACFP and Novamin. Results: Both the experimental groups showed very high significant differences between Ca/P ratios of remineralized samples. Conclusion: Even though both CPP-ACFP and Novamin showed remineralization potential, remineralization was found to be higher in the samples treated with CPP-ACFP.</description><subject>Acids</subject><subject>Calcification</subject><subject>Calcium phosphates</subject><subject>Casein</subject><subject>Chloride</subject><subject>Comparative analysis</subject><subject>Demineralization</subject><subject>Dental caries</subject><subject>Dental enamel</subject><subject>Dental research</subject><subject>Dentistry</subject><subject>Enamel</subject><subject>Enamel and enameling</subject><subject>Fluorides</subject><subject>Fluorspar</subject><subject>Mineralization</subject><subject>Original</subject><subject>Orthodontics</subject><subject>Physiological aspects</subject><subject>Premolars</subject><subject>Public health</subject><subject>Remineralization</subject><subject>Scanning electron microscopy</subject><subject>Sodium</subject><subject>Statistical analysis</subject><issn>0976-237X</issn><issn>0976-2361</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptkl9r2zAUxc3YWEvXx70OwWDsxZkk27K9h0EI-1Mo7GWDvQlZum7UypInyQnZd9t3m0zStBm1EZbv_enIPjpZ9prgRUlw8UFKtUiD04aT5ll2jtua5bRg5PlxXv86yy5DuMXpKtoSV-XL7Iy2LaM1q86zvys3jMKLqDeAYCPMlKbOItcjD4O24IXRf_a10UWwUQszd6UIoFNt7UIaI4xRK8iRGJxP71NIgJF6GlBvJudT74CKCEhYhazbiKSPkq7wUfdaJmGzQ-phV1BoPQ3CIrBiAPMRLS26smijo3coxEntXmUvemECXB6eF9nPL59_rL7l19-_Xq2W17msWBPzulKspqouq74jlexUSTGQXlBZiobWPWFFJ1Q790lHlIAaKylJW-GWlUXbFRfZp73uOHUDKJlsSF_IR68H4XfcCc1PO1av-Y3bcIYxa-omCbw_CHj3e4IQ-aCDBGOEhWQWp5gVNSEFpQl9-x966yZv0-8lqkoEKfAj6kYY4Nr2Lu0rZ1G-rEpKWsbYTC2eoNI9uyydhV6n-smCd48WrEGYuA7OTPP5h1Mw34PSuxA89EczCOZzNvmcy2M2E__msYNH-j6JDxZvnYngw52ZtuB5Yu-s2z6tyquG3-e3-AcMbfs-</recordid><startdate>20180601</startdate><enddate>20180601</enddate><creator>Manoharan, Vidya</creator><creator>Kumar, R</creator><creator>Sivanraj, Arun</creator><creator>Arumugam, Selva</creator><general>Wolters Kluwer India Pvt. Ltd</general><general>Medknow Publications and Media Pvt. Ltd</general><general>Medknow Publications & Media Pvt. Ltd</general><general>Medknow Publications & Media Pvt Ltd</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20180601</creationdate><title>Comparative evaluation of remineralization potential of casein phosphopeptide- amorphous calcium fluoride phosphate and novamin on artificially demineralized human enamel: An In vitro study</title><author>Manoharan, Vidya ; Kumar, R ; Sivanraj, Arun ; Arumugam, Selva</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c568t-75d672d745fb15cbd420e1fa2c4a827f163bad9745f1b1dae70dcc195096439b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Acids</topic><topic>Calcification</topic><topic>Calcium phosphates</topic><topic>Casein</topic><topic>Chloride</topic><topic>Comparative analysis</topic><topic>Demineralization</topic><topic>Dental caries</topic><topic>Dental enamel</topic><topic>Dental research</topic><topic>Dentistry</topic><topic>Enamel</topic><topic>Enamel and enameling</topic><topic>Fluorides</topic><topic>Fluorspar</topic><topic>Mineralization</topic><topic>Original</topic><topic>Orthodontics</topic><topic>Physiological aspects</topic><topic>Premolars</topic><topic>Public health</topic><topic>Remineralization</topic><topic>Scanning electron microscopy</topic><topic>Sodium</topic><topic>Statistical analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Manoharan, Vidya</creatorcontrib><creatorcontrib>Kumar, R</creatorcontrib><creatorcontrib>Sivanraj, Arun</creatorcontrib><creatorcontrib>Arumugam, Selva</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Contemporary clinical dentistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Manoharan, Vidya</au><au>Kumar, R</au><au>Sivanraj, Arun</au><au>Arumugam, Selva</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparative evaluation of remineralization potential of casein phosphopeptide- amorphous calcium fluoride phosphate and novamin on artificially demineralized human enamel: An In vitro study</atitle><jtitle>Contemporary clinical dentistry</jtitle><addtitle>Contemp Clin Dent</addtitle><date>2018-06-01</date><risdate>2018</risdate><volume>9</volume><issue>5</issue><spage>58</spage><epage>63</epage><pages>58-63</pages><issn>0976-237X</issn><eissn>0976-2361</eissn><abstract>Aim: This study aimed to quantitatively compare the remineralization potential of casein phosphopeptide-amorphous calcium fluoride phosphate (CPP-ACFP) and Novamin on artificially induced enamel subsurface lesions using scanning electron microscope-energy dispersive X-ray (SEM-EDX). Materials and Methods: Enamel specimens were prepared from seventy caries-free premolars and were kept for demineralization for 4 days. Following demineralization, enamel specimens were assigned to three groups: (1) Control group, (2) Group with CPP-ACFP-containing toothpaste, and (3) Group with Novamin-containing toothpaste. Further, both the experimental groups (CPP-ACFP group and Novamin) were then divided into three subgroups based on the duration of re-mineralization as follows: (a) 7 days, (b) 14 days, and (c) 21 days. Enamel specimens of experimental groups were then subjected to SEM-EDX to evaluate mineral content after treating with CPP-ACFP and Novamin. Results: Both the experimental groups showed very high significant differences between Ca/P ratios of remineralized samples. Conclusion: Even though both CPP-ACFP and Novamin showed remineralization potential, remineralization was found to be higher in the samples treated with CPP-ACFP.</abstract><cop>India</cop><pub>Wolters Kluwer India Pvt. Ltd</pub><pmid>29962765</pmid><doi>10.4103/ccd.ccd_28_18</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0976-237X |
| ispartof | Contemporary clinical dentistry, 2018-06, Vol.9 (5), p.58-63 |
| issn | 0976-237X 0976-2361 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6006878 |
| source | Medknow Open Access Medical Journals; DOAJ Directory of Open Access Journals; PubMed Central Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Acids Calcification Calcium phosphates Casein Chloride Comparative analysis Demineralization Dental caries Dental enamel Dental research Dentistry Enamel Enamel and enameling Fluorides Fluorspar Mineralization Original Orthodontics Physiological aspects Premolars Public health Remineralization Scanning electron microscopy Sodium Statistical analysis |
| title | Comparative evaluation of remineralization potential of casein phosphopeptide- amorphous calcium fluoride phosphate and novamin on artificially demineralized human enamel: An In vitro study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T02%3A56%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Comparative%20evaluation%20of%20remineralization%20potential%20of%20casein%20phosphopeptide-%20amorphous%20calcium%20fluoride%20phosphate%20and%20novamin%20on%20artificially%20demineralized%20human%20enamel:%20An%20In%20vitro%20study&rft.jtitle=Contemporary%20clinical%20dentistry&rft.au=Manoharan,%20Vidya&rft.date=2018-06-01&rft.volume=9&rft.issue=5&rft.spage=58&rft.epage=63&rft.pages=58-63&rft.issn=0976-237X&rft.eissn=0976-2361&rft_id=info:doi/10.4103/ccd.ccd_28_18&rft_dat=%3Cgale_pubme%3EA542196662%3C/gale_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2053221302&rft_id=info:pmid/29962765&rft_galeid=A542196662&rfr_iscdi=true |