Mass Spectrometry-Based Method to Study Inhibitor-Induced Metabolic Redirection in the Central Metabolism of Cancer Cells

Cancer cells often respond to chemotherapeutic inhibitors by redirecting carbon flow in the central metabolism. To understand the metabolic redirections of inhibitor treatment on cancer cells, this study established a 13C-metabolic flux analysis (13C-MFA)-based method to evaluate metabolic redirecti...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Mass Spectrometry 2018/06/14, Vol.7(1), pp.A0067-A0067
Hauptverfasser:	Araki, Chie, Okahashi, Nobuyuki, Maeda, Kousuke, Shimizu, Hiroshi, Matsuda, Fumio
Format:	Artikel
Sprache:	eng
Schlagworte:	13C-metabolic flux analysis cancer cells central metabolism isotope abundance metabolic redirection Original
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!