Subcortical structural connectivity of insular subregions
Hidden beneath the Sylvian fissure and sometimes considered as the fifth lobe of the brain, the insula plays a multi-modal role from its strategic location. Previous structural studies have reported cortico-cortical connections with the frontal, temporal, parietal and occipital lobes, but only a few...
Gespeichert in:
Veröffentlicht in: | Scientific reports 2018-06, Vol.8 (1), p.8596-12, Article 8596 |
---|---|
Hauptverfasser: | , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 12 |
---|---|
container_issue | 1 |
container_start_page | 8596 |
container_title | Scientific reports |
container_volume | 8 |
creator | Ghaziri, Jimmy Tucholka, Alan Girard, Gabriel Boucher, Olivier Houde, Jean-Christophe Descoteaux, Maxime Obaid, Sami Gilbert, Guillaume Rouleau, Isabelle Nguyen, Dang Khoa |
description | Hidden beneath the Sylvian fissure and sometimes considered as the fifth lobe of the brain, the insula plays a multi-modal role from its strategic location. Previous structural studies have reported cortico-cortical connections with the frontal, temporal, parietal and occipital lobes, but only a few have looked at its connections with subcortical structures. The insular cortex plays a role in a wide range of functions including processing of visceral and somatosensory inputs, olfaction, audition, language, motivation, craving, addiction and emotions such as pain, empathy and disgust. These functions implicate numerous subcortical structures, as suggested by various functional studies. Based on these premises, we explored the structural connectivity of insular ROIs with the thalamus, amygdala, hippocampus, putamen, globus pallidus, caudate nucleus and nucleus accumbens. More precisely, we were interested in unraveling the specific areas of the insula connected to these subcortical structures. By using state-of-the-art HARDI tractography algorithm, we explored here the subcortical connectivity of the insula. |
doi_str_mv | 10.1038/s41598-018-26995-0 |
format | Article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5988839</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2050459991</sourcerecordid><originalsourceid>FETCH-LOGICAL-c540t-f384634e9ffdeaf5835d99b7572ca87f69061784adb4edecb052635c15d9098f3</originalsourceid><addsrcrecordid>eNp9kclKBDEQhoMoKuO8gAcZ8OKlNUunO3URRNxA8KCeQzqdjJGeRJOOMG9vdNwP5pKC-uqv5Udol-BDgpk4SjXhICpMREUbAF7hNbRNcc0ryihd_xFvoWlKj7g8TqEmsIm2KIiWUkK3EdzmToc4Oq2GWRpj1mOOJdTBe6NH9-LG5SzYmfMpDyrOUu6imbvg0w7asGpIZvrxT9D9-dnd6WV1fXNxdXpyXWle47GyTNQNqw1Y2xtluWC8B-ha3lKtRGsbwA1pRa36rja90V2ZsmFck4JhEJZN0PFK9yl3C9Nr48cyoHyKbqHiUgbl5O-Mdw9yHl5kOY8QDIrAwYdADM_ZpFEuXNJmGJQ3ISdJMSe4AUbagu7_QR9Djr6s90aVgwIAKRRdUTqGlKKxX8MQLN_MkStzZDFHvpsjcSna-7nGV8mnFQVgKyCVlJ-b-N37H9lXJXmbFw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2050459991</pqid></control><display><type>article</type><title>Subcortical structural connectivity of insular subregions</title><source>DOAJ Directory of Open Access Journals</source><source>Springer Nature OA Free Journals</source><source>Nature Free</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Ghaziri, Jimmy ; Tucholka, Alan ; Girard, Gabriel ; Boucher, Olivier ; Houde, Jean-Christophe ; Descoteaux, Maxime ; Obaid, Sami ; Gilbert, Guillaume ; Rouleau, Isabelle ; Nguyen, Dang Khoa</creator><creatorcontrib>Ghaziri, Jimmy ; Tucholka, Alan ; Girard, Gabriel ; Boucher, Olivier ; Houde, Jean-Christophe ; Descoteaux, Maxime ; Obaid, Sami ; Gilbert, Guillaume ; Rouleau, Isabelle ; Nguyen, Dang Khoa</creatorcontrib><description>Hidden beneath the Sylvian fissure and sometimes considered as the fifth lobe of the brain, the insula plays a multi-modal role from its strategic location. Previous structural studies have reported cortico-cortical connections with the frontal, temporal, parietal and occipital lobes, but only a few have looked at its connections with subcortical structures. The insular cortex plays a role in a wide range of functions including processing of visceral and somatosensory inputs, olfaction, audition, language, motivation, craving, addiction and emotions such as pain, empathy and disgust. These functions implicate numerous subcortical structures, as suggested by various functional studies. Based on these premises, we explored the structural connectivity of insular ROIs with the thalamus, amygdala, hippocampus, putamen, globus pallidus, caudate nucleus and nucleus accumbens. More precisely, we were interested in unraveling the specific areas of the insula connected to these subcortical structures. By using state-of-the-art HARDI tractography algorithm, we explored here the subcortical connectivity of the insula.</description><identifier>ISSN: 2045-2322</identifier><identifier>EISSN: 2045-2322</identifier><identifier>DOI: 10.1038/s41598-018-26995-0</identifier><identifier>PMID: 29872212</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>59/57 ; 692/617/375/178 ; 692/698/1688/64 ; Addictions ; Algorithms ; Amygdala ; Caudate nucleus ; Cortex (insular) ; Globus pallidus ; Humanities and Social Sciences ; Magnetic resonance imaging ; Motivation ; multidisciplinary ; Neural networks ; Nucleus accumbens ; Olfaction ; Pain ; Putamen ; Science ; Science (multidisciplinary) ; Somatosensory cortex ; Temporal lobe ; Thalamus</subject><ispartof>Scientific reports, 2018-06, Vol.8 (1), p.8596-12, Article 8596</ispartof><rights>The Author(s) 2018</rights><rights>2018. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c540t-f384634e9ffdeaf5835d99b7572ca87f69061784adb4edecb052635c15d9098f3</citedby><cites>FETCH-LOGICAL-c540t-f384634e9ffdeaf5835d99b7572ca87f69061784adb4edecb052635c15d9098f3</cites><orcidid>0000-0003-3026-021X ; 0000-0002-5781-3104</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988839/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988839/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,41120,42189,51576,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29872212$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ghaziri, Jimmy</creatorcontrib><creatorcontrib>Tucholka, Alan</creatorcontrib><creatorcontrib>Girard, Gabriel</creatorcontrib><creatorcontrib>Boucher, Olivier</creatorcontrib><creatorcontrib>Houde, Jean-Christophe</creatorcontrib><creatorcontrib>Descoteaux, Maxime</creatorcontrib><creatorcontrib>Obaid, Sami</creatorcontrib><creatorcontrib>Gilbert, Guillaume</creatorcontrib><creatorcontrib>Rouleau, Isabelle</creatorcontrib><creatorcontrib>Nguyen, Dang Khoa</creatorcontrib><title>Subcortical structural connectivity of insular subregions</title><title>Scientific reports</title><addtitle>Sci Rep</addtitle><addtitle>Sci Rep</addtitle><description>Hidden beneath the Sylvian fissure and sometimes considered as the fifth lobe of the brain, the insula plays a multi-modal role from its strategic location. Previous structural studies have reported cortico-cortical connections with the frontal, temporal, parietal and occipital lobes, but only a few have looked at its connections with subcortical structures. The insular cortex plays a role in a wide range of functions including processing of visceral and somatosensory inputs, olfaction, audition, language, motivation, craving, addiction and emotions such as pain, empathy and disgust. These functions implicate numerous subcortical structures, as suggested by various functional studies. Based on these premises, we explored the structural connectivity of insular ROIs with the thalamus, amygdala, hippocampus, putamen, globus pallidus, caudate nucleus and nucleus accumbens. More precisely, we were interested in unraveling the specific areas of the insula connected to these subcortical structures. By using state-of-the-art HARDI tractography algorithm, we explored here the subcortical connectivity of the insula.</description><subject>59/57</subject><subject>692/617/375/178</subject><subject>692/698/1688/64</subject><subject>Addictions</subject><subject>Algorithms</subject><subject>Amygdala</subject><subject>Caudate nucleus</subject><subject>Cortex (insular)</subject><subject>Globus pallidus</subject><subject>Humanities and Social Sciences</subject><subject>Magnetic resonance imaging</subject><subject>Motivation</subject><subject>multidisciplinary</subject><subject>Neural networks</subject><subject>Nucleus accumbens</subject><subject>Olfaction</subject><subject>Pain</subject><subject>Putamen</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Somatosensory cortex</subject><subject>Temporal lobe</subject><subject>Thalamus</subject><issn>2045-2322</issn><issn>2045-2322</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kclKBDEQhoMoKuO8gAcZ8OKlNUunO3URRNxA8KCeQzqdjJGeRJOOMG9vdNwP5pKC-uqv5Udol-BDgpk4SjXhICpMREUbAF7hNbRNcc0ryihd_xFvoWlKj7g8TqEmsIm2KIiWUkK3EdzmToc4Oq2GWRpj1mOOJdTBe6NH9-LG5SzYmfMpDyrOUu6imbvg0w7asGpIZvrxT9D9-dnd6WV1fXNxdXpyXWle47GyTNQNqw1Y2xtluWC8B-ha3lKtRGsbwA1pRa36rja90V2ZsmFck4JhEJZN0PFK9yl3C9Nr48cyoHyKbqHiUgbl5O-Mdw9yHl5kOY8QDIrAwYdADM_ZpFEuXNJmGJQ3ISdJMSe4AUbagu7_QR9Djr6s90aVgwIAKRRdUTqGlKKxX8MQLN_MkStzZDFHvpsjcSna-7nGV8mnFQVgKyCVlJ-b-N37H9lXJXmbFw</recordid><startdate>20180605</startdate><enddate>20180605</enddate><creator>Ghaziri, Jimmy</creator><creator>Tucholka, Alan</creator><creator>Girard, Gabriel</creator><creator>Boucher, Olivier</creator><creator>Houde, Jean-Christophe</creator><creator>Descoteaux, Maxime</creator><creator>Obaid, Sami</creator><creator>Gilbert, Guillaume</creator><creator>Rouleau, Isabelle</creator><creator>Nguyen, Dang Khoa</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>C6C</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-3026-021X</orcidid><orcidid>https://orcid.org/0000-0002-5781-3104</orcidid></search><sort><creationdate>20180605</creationdate><title>Subcortical structural connectivity of insular subregions</title><author>Ghaziri, Jimmy ; Tucholka, Alan ; Girard, Gabriel ; Boucher, Olivier ; Houde, Jean-Christophe ; Descoteaux, Maxime ; Obaid, Sami ; Gilbert, Guillaume ; Rouleau, Isabelle ; Nguyen, Dang Khoa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c540t-f384634e9ffdeaf5835d99b7572ca87f69061784adb4edecb052635c15d9098f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>59/57</topic><topic>692/617/375/178</topic><topic>692/698/1688/64</topic><topic>Addictions</topic><topic>Algorithms</topic><topic>Amygdala</topic><topic>Caudate nucleus</topic><topic>Cortex (insular)</topic><topic>Globus pallidus</topic><topic>Humanities and Social Sciences</topic><topic>Magnetic resonance imaging</topic><topic>Motivation</topic><topic>multidisciplinary</topic><topic>Neural networks</topic><topic>Nucleus accumbens</topic><topic>Olfaction</topic><topic>Pain</topic><topic>Putamen</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Somatosensory cortex</topic><topic>Temporal lobe</topic><topic>Thalamus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ghaziri, Jimmy</creatorcontrib><creatorcontrib>Tucholka, Alan</creatorcontrib><creatorcontrib>Girard, Gabriel</creatorcontrib><creatorcontrib>Boucher, Olivier</creatorcontrib><creatorcontrib>Houde, Jean-Christophe</creatorcontrib><creatorcontrib>Descoteaux, Maxime</creatorcontrib><creatorcontrib>Obaid, Sami</creatorcontrib><creatorcontrib>Gilbert, Guillaume</creatorcontrib><creatorcontrib>Rouleau, Isabelle</creatorcontrib><creatorcontrib>Nguyen, Dang Khoa</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Scientific reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ghaziri, Jimmy</au><au>Tucholka, Alan</au><au>Girard, Gabriel</au><au>Boucher, Olivier</au><au>Houde, Jean-Christophe</au><au>Descoteaux, Maxime</au><au>Obaid, Sami</au><au>Gilbert, Guillaume</au><au>Rouleau, Isabelle</au><au>Nguyen, Dang Khoa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Subcortical structural connectivity of insular subregions</atitle><jtitle>Scientific reports</jtitle><stitle>Sci Rep</stitle><addtitle>Sci Rep</addtitle><date>2018-06-05</date><risdate>2018</risdate><volume>8</volume><issue>1</issue><spage>8596</spage><epage>12</epage><pages>8596-12</pages><artnum>8596</artnum><issn>2045-2322</issn><eissn>2045-2322</eissn><abstract>Hidden beneath the Sylvian fissure and sometimes considered as the fifth lobe of the brain, the insula plays a multi-modal role from its strategic location. Previous structural studies have reported cortico-cortical connections with the frontal, temporal, parietal and occipital lobes, but only a few have looked at its connections with subcortical structures. The insular cortex plays a role in a wide range of functions including processing of visceral and somatosensory inputs, olfaction, audition, language, motivation, craving, addiction and emotions such as pain, empathy and disgust. These functions implicate numerous subcortical structures, as suggested by various functional studies. Based on these premises, we explored the structural connectivity of insular ROIs with the thalamus, amygdala, hippocampus, putamen, globus pallidus, caudate nucleus and nucleus accumbens. More precisely, we were interested in unraveling the specific areas of the insula connected to these subcortical structures. By using state-of-the-art HARDI tractography algorithm, we explored here the subcortical connectivity of the insula.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>29872212</pmid><doi>10.1038/s41598-018-26995-0</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0003-3026-021X</orcidid><orcidid>https://orcid.org/0000-0002-5781-3104</orcidid><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 2045-2322 |
ispartof | Scientific reports, 2018-06, Vol.8 (1), p.8596-12, Article 8596 |
issn | 2045-2322 2045-2322 |
language | eng |
recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5988839 |
source | DOAJ Directory of Open Access Journals; Springer Nature OA Free Journals; Nature Free; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
subjects | 59/57 692/617/375/178 692/698/1688/64 Addictions Algorithms Amygdala Caudate nucleus Cortex (insular) Globus pallidus Humanities and Social Sciences Magnetic resonance imaging Motivation multidisciplinary Neural networks Nucleus accumbens Olfaction Pain Putamen Science Science (multidisciplinary) Somatosensory cortex Temporal lobe Thalamus |
title | Subcortical structural connectivity of insular subregions |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T00%3A18%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Subcortical%20structural%20connectivity%20of%20insular%20subregions&rft.jtitle=Scientific%20reports&rft.au=Ghaziri,%20Jimmy&rft.date=2018-06-05&rft.volume=8&rft.issue=1&rft.spage=8596&rft.epage=12&rft.pages=8596-12&rft.artnum=8596&rft.issn=2045-2322&rft.eissn=2045-2322&rft_id=info:doi/10.1038/s41598-018-26995-0&rft_dat=%3Cproquest_pubme%3E2050459991%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2050459991&rft_id=info:pmid/29872212&rfr_iscdi=true |