Concurrent, but not sequential, PD-1 blockade with a DNA vaccine elicits anti-tumor responses in patients with metastatic, castration-resistant prostate cancer

T-cell checkpoint inhibitors have demonstrated dramatic clinical activity against multiple cancer types, however little activity in patients with prostate cancer. Conversely, an anti-tumor vaccine was approved for the treatment of prostate cancer, having demonstrated an improvement in overall surviv...

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Veröffentlicht in:Oncotarget 2018-05, Vol.9 (39), p.25586-25596
Hauptverfasser: McNeel, Douglas G, Eickhoff, Jens C, Wargowski, Ellen, Zahm, Christopher, Staab, Mary Jane, Straus, Jane, Liu, Glenn
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Sprache:eng
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