Antifungal Efficacy and the Mechanical Properties of Soft Liners against Candida albicans after the Incorporation of Garlic and Neem: An In vitro Study
To evaluate the growth inhibition of , in the soft-liner material and Shore A hardness from resin-based denture soft lining materials modified by neem or garlic incorporation. Resin discs were prepared with poly methyl methacrylate (PMMA) and soft liners incorporated with varying concentrations of n...
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| Veröffentlicht in: | Journal of International Society of Preventive & Community Dentistry 2018-05, Vol.8 (3), p.212-217 |
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| container_title | Journal of International Society of Preventive & Community Dentistry |
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| creator | Kumar, Seenivasan Madhan Kumar, V Anand Natarajan, Parathasarthy Sreenivasan, Gayathri |
| description | To evaluate the
growth inhibition of
, in the soft-liner material and Shore A hardness from resin-based denture soft lining materials modified by neem or garlic incorporation.
Resin discs were prepared with poly methyl methacrylate (PMMA) and soft liners incorporated with varying concentrations of neem or garlic. For antifungal activity, resin discs were placed on agar plates inoculated with
and were evaluated after 2, 4, and 7 days using the streaking method. The hardness of the PMMA was evaluated with the use of Shore A at 2, 4, and 7 days. Data were statistically processed by SPSS software (IBM Company, Chicago, USA) using Kruskal-Wallis test, and
comparisons were done using Dunn's test. |
| doi_str_mv | 10.4103/jispcd.JISPCD_343_17 |
| format | Article |
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growth inhibition of
, in the soft-liner material and Shore A hardness from resin-based denture soft lining materials modified by neem or garlic incorporation.
Resin discs were prepared with poly methyl methacrylate (PMMA) and soft liners incorporated with varying concentrations of neem or garlic. For antifungal activity, resin discs were placed on agar plates inoculated with
and were evaluated after 2, 4, and 7 days using the streaking method. The hardness of the PMMA was evaluated with the use of Shore A at 2, 4, and 7 days. Data were statistically processed by SPSS software (IBM Company, Chicago, USA) using Kruskal-Wallis test, and
comparisons were done using Dunn's test.
<0.05 was considered statistically significant.
Neem and garlic added to PMMA soft liner had an inhibitory effect on
. Both the neem and garlic when added showed positive results against
when compared to the control group. The soft liner hardness increased statistically by time but not for the different plant extract concentrations.
Within the limitations of this
study, it was found that neem and garlic can be used as an additive to tissue conditioner to reduce the adherence of
without significantly affecting the hardness of the heat-polymerized acrylic resin.</description><identifier>ISSN: 2231-0762</identifier><identifier>EISSN: 2250-1002</identifier><identifier>DOI: 10.4103/jispcd.JISPCD_343_17</identifier><identifier>PMID: 29911057</identifier><language>eng</language><publisher>India: Medknow Publications & Media Pvt. Ltd</publisher><subject>Allium sativum ; Antifungal activity ; Antifungal agents ; Antimicrobial agents ; Azadirachta indica ; Biofilms ; Candida ; Candida albicans ; Garlic ; Mechanical properties ; Neem ; Original ; Plant extracts ; Polymethylmethacrylate ; Statistical analysis</subject><ispartof>Journal of International Society of Preventive & Community Dentistry, 2018-05, Vol.8 (3), p.212-217</ispartof><rights>Copyright Medknow Publications & Media Pvt. Ltd. May/Jun 2018</rights><rights>Copyright: © 2018 Journal of International Society of Preventive and Community Dentistry 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c436t-be2e54b98c1462900573c82bd37159c750a5fdac3cf50d0f8e114f0cda8149153</citedby><cites>FETCH-LOGICAL-c436t-be2e54b98c1462900573c82bd37159c750a5fdac3cf50d0f8e114f0cda8149153</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985676/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985676/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,725,778,782,883,27911,27912,53778,53780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29911057$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kumar, Seenivasan Madhan</creatorcontrib><creatorcontrib>Kumar, V Anand</creatorcontrib><creatorcontrib>Natarajan, Parathasarthy</creatorcontrib><creatorcontrib>Sreenivasan, Gayathri</creatorcontrib><title>Antifungal Efficacy and the Mechanical Properties of Soft Liners against Candida albicans after the Incorporation of Garlic and Neem: An In vitro Study</title><title>Journal of International Society of Preventive & Community Dentistry</title><addtitle>J Int Soc Prev Community Dent</addtitle><description>To evaluate the
growth inhibition of
, in the soft-liner material and Shore A hardness from resin-based denture soft lining materials modified by neem or garlic incorporation.
Resin discs were prepared with poly methyl methacrylate (PMMA) and soft liners incorporated with varying concentrations of neem or garlic. For antifungal activity, resin discs were placed on agar plates inoculated with
and were evaluated after 2, 4, and 7 days using the streaking method. The hardness of the PMMA was evaluated with the use of Shore A at 2, 4, and 7 days. Data were statistically processed by SPSS software (IBM Company, Chicago, USA) using Kruskal-Wallis test, and
comparisons were done using Dunn's test.
<0.05 was considered statistically significant.
Neem and garlic added to PMMA soft liner had an inhibitory effect on
. Both the neem and garlic when added showed positive results against
when compared to the control group. The soft liner hardness increased statistically by time but not for the different plant extract concentrations.
Within the limitations of this
study, it was found that neem and garlic can be used as an additive to tissue conditioner to reduce the adherence of
without significantly affecting the hardness of the heat-polymerized acrylic resin.</description><subject>Allium sativum</subject><subject>Antifungal activity</subject><subject>Antifungal agents</subject><subject>Antimicrobial agents</subject><subject>Azadirachta indica</subject><subject>Biofilms</subject><subject>Candida</subject><subject>Candida albicans</subject><subject>Garlic</subject><subject>Mechanical properties</subject><subject>Neem</subject><subject>Original</subject><subject>Plant extracts</subject><subject>Polymethylmethacrylate</subject><subject>Statistical analysis</subject><issn>2231-0762</issn><issn>2250-1002</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNpVkd1qGzEQhZfSkoQ0bxCKoNeb6ndX24uCcdLUxW0DTq6FVj-2zFraStqAn6SvWzlOQ6MbiZnznRlxquoSwSuKIPm0dWlU-ur7YnU3vxaEEoHaN9UZxgzWCEL89vAmqIZtg0-ri5S2sJyG065tTqpT3HUIQdaeVX9mPjs7-bUcwI21Tkm1B9JrkDcG_DBqI32pDeAuhtHE7EwCwYJVsBksnTcxAbmWzqcM5oVyWgI59IXwpWGziU8-C69CHEOU2QV_4G9lHJx6mvPTmN1nMPNFBB5djgGs8qT376t3Vg7JXDzf59XD15v7-bd6-et2MZ8ta0VJk-veYMNo33GFaIM7WP5EFMe9Ji1inWoZlMxqqYiyDGpouUGIWqi05Ih2iJHz6svRd5z6ndHK-BzlIMbodjLuRZBOvO54txHr8ChYx1nTNsXg47NBDL8nk7LYhin6srPAkCIGOeewqOhRpWJIKRr7MgFBcUhUHBMVrxIt2If_t3uB_uVH_gJczaF4</recordid><startdate>20180501</startdate><enddate>20180501</enddate><creator>Kumar, Seenivasan Madhan</creator><creator>Kumar, V Anand</creator><creator>Natarajan, Parathasarthy</creator><creator>Sreenivasan, Gayathri</creator><general>Medknow Publications & Media Pvt. 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growth inhibition of
, in the soft-liner material and Shore A hardness from resin-based denture soft lining materials modified by neem or garlic incorporation.
Resin discs were prepared with poly methyl methacrylate (PMMA) and soft liners incorporated with varying concentrations of neem or garlic. For antifungal activity, resin discs were placed on agar plates inoculated with
and were evaluated after 2, 4, and 7 days using the streaking method. The hardness of the PMMA was evaluated with the use of Shore A at 2, 4, and 7 days. Data were statistically processed by SPSS software (IBM Company, Chicago, USA) using Kruskal-Wallis test, and
comparisons were done using Dunn's test.
<0.05 was considered statistically significant.
Neem and garlic added to PMMA soft liner had an inhibitory effect on
. Both the neem and garlic when added showed positive results against
when compared to the control group. The soft liner hardness increased statistically by time but not for the different plant extract concentrations.
Within the limitations of this
study, it was found that neem and garlic can be used as an additive to tissue conditioner to reduce the adherence of
without significantly affecting the hardness of the heat-polymerized acrylic resin.</abstract><cop>India</cop><pub>Medknow Publications & Media Pvt. Ltd</pub><pmid>29911057</pmid><doi>10.4103/jispcd.JISPCD_343_17</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2231-0762 |
| ispartof | Journal of International Society of Preventive & Community Dentistry, 2018-05, Vol.8 (3), p.212-217 |
| issn | 2231-0762 2250-1002 |
| language | eng |
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| source | Medknow Open Access Medical Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; PubMed Central |
| subjects | Allium sativum Antifungal activity Antifungal agents Antimicrobial agents Azadirachta indica Biofilms Candida Candida albicans Garlic Mechanical properties Neem Original Plant extracts Polymethylmethacrylate Statistical analysis |
| title | Antifungal Efficacy and the Mechanical Properties of Soft Liners against Candida albicans after the Incorporation of Garlic and Neem: An In vitro Study |
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