Facilitation of kindling epileptogenesis by chronic stress may be mediated by intestinal microbiome

There has been growing interest in the role of intestinal microbiome in brain disorders. We examined whether dysbiosis can predispose to epilepsy. The study was performed in female and male Sprague-Dawley rats. To induce dysbiosis, the rats were subjected to chronic restraint stress (two 2-h long se...

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Veröffentlicht in:	Epilepsia open 2018-06, Vol.3 (2), p.290-294
Hauptverfasser:	Medel-Matus, Jesús-Servando, Shin, Don, Dorfman, Edward, Sankar, Raman, Mazarati, Andrey
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics Convulsions & seizures Drinking water Epilepsy Food Inflammation Microbiota Permeability Plastics Short Software Stress Transplants & implants Variance analysis
Online-Zugang:	Volltext
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