High salt induces P-glycoprotein mediated treatment resistance in breast cancer cells through store operated calcium influx

Recent evidence from our laboratory has demonstrated that high salt (Δ0.05 M NaCl) induced inflammatory response and cancer cell proliferation through salt inducible kinase-3 (SIK3) upregulation. As calcium influx is known to effect inflammatory response and drug resistance, we examined the impact o...

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Veröffentlicht in:Oncotarget 2018-05, Vol.9 (38), p.25193-25205
Hauptverfasser: Babaer, Duaa, Amara, Suneetha, Ivy, Michael, Zhao, Yan, Lammers, Philip E, Titze, Jens M, Tiriveedhi, Venkataswarup
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Sprache:eng
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