Aluminum Adjuvant-Containing Vaccines in the Context of the Hygiene Hypothesis: A Risk Factor for Eosinophilia and Allergy in a Genetically Susceptible Subpopulation?

There are similarities between the immune response following immunization with aluminum adjuvants and the immune response elicited by some helminthic parasites, including stimulation of immunoglobulin E (IgE) and eosinophilia. Immunization with aluminum adjuvants, as with helminth infection, induces...

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Veröffentlicht in:	International journal of environmental research and public health 2018-05, Vol.15 (5), p.901
Hauptverfasser:	Terhune, Todd D, Deth, Richard C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants Adjuvants, Immunologic - administration & dosage Allergic diseases Allergies Aluminum Aluminum - administration & dosage Animals Antigens Asthma Atopy Blood diseases Bone marrow Composition Cytokines Eosinophilia Eosinophilia - genetics Eosinophilia - immunology Food allergies Gene expression Genetic Predisposition to Disease Health risks Helminthiasis - immunology Humans Hygiene Hygiene Hypothesis Hypersensitivity Hypersensitivity - genetics Hypersensitivity - immunology Hypotheses Immune response Immune system Immunization Immunoglobulin E Lungs Lymphocytes Lymphocytes T Microbiota Morbidity Parasites Potassium Review Risk Factors Spleen Studies Tetanus Vaccines Vaccines - administration & dosage Whooping cough
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