A Phage Lysin Fused to a Cell-Penetrating Peptide Kills Intracellular Methicillin-Resistant Staphylococcus aureus in Keratinocytes and Has Potential as a Treatment for Skin Infections in Mice

is the main pathogen that causes skin and skin structure infections and is able to survive and persist in keratinocytes of the epidermis. Since the evolution of multidrug-resistant bacteria, the use of phages and their lysins has presented a promising alternative approach to treatment. In this study...

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Veröffentlicht in:Applied and environmental microbiology 2018-06, Vol.84 (12), p.e00380-18
Hauptverfasser: Wang, ZhaoFei, Kong, LiCheng, Liu, Yang, Fu, Qiang, Cui, ZeLin, Wang, Jian, Ma, JingJiao, Wang, HengAn, Yan, YaXian, Sun, JianHe
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Sprache:eng
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