The CD11a and Endothelial Protein C Receptor Marker Combination Simplifies and Improves the Purification of Mouse Hematopoietic Stem Cells

Hematopoietic stem cells (HSCs) are the self‐renewing multipotent progenitors to all blood cell types. Identification and isolation of HSCs for study has depended on the expression of combinations of surface markers on HSCs that reliably distinguish them from other cell types. However, the increasin...

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Veröffentlicht in:	Stem cells translational medicine 2018-06, Vol.7 (6), p.468-476
Hauptverfasser:	Karimzadeh, Alborz, Scarfone, Vanessa M., Varady, Erika, Chao, Connie, Grathwohl, Karin, Fathman, John W., Fruman, David A., Serwold, Thomas, Inlay, Matthew A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers - metabolism Blood Bone marrow Bone Marrow Cells - cytology Bone Marrow Cells - drug effects Bone Marrow Cells - metabolism Bone marrow transplantation CD11a antigen CD11a Antigen - metabolism CD150 antigen Cell surface markers Cold Endothelial Protein C Receptor - metabolism Endothelium Flow cytometry Flow Cytometry - methods Graft vs Host Disease Hematopoietic Disorders Hematopoietic Regeneration Hematopoietic Stem Cell Transplantation Hematopoietic stem cells Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - metabolism Hematopoietic Stem/Progenitor Cells Immunoglobulins Laboratory animals Lipopolysaccharides - toxicity long‐term repopulation Mice Mice, Inbred C57BL Novel Cell Markers Poly I-C - toxicity Population Protein C Protein purification Proteins Statistical analysis Stem cell transplantation Stem cells Surface markers Tissue-specific Progenitor and Stem cells Translational s and Reviews
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