Furin inhibitor protects against neuronal cell death induced by activated NMDA receptors

The proprotein convertases (PCs) act as serine proteases and are known to convert diverse precursor proteins into their active forms. Among the PCs, furin has been considered to play a crucial role not only in embryogenesis, but also in the initiation and progression of certain pathologic conditions...

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Veröffentlicht in:Scientific reports 2018-03, Vol.8 (1), p.5212-9, Article 5212
Hauptverfasser: Yamada, Mariko, Hayashi, Hideki, Yuuki, Moe, Matsushima, Nahoko, Yuan, Bo, Takagi, Norio
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Sprache:eng
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