Modulation of TRPA1 channel activity by Cdk5 in sensory neurons

Transient receptor potential cation channel, subfamily A, member 1 (TRPA1), is activated by a broad range of noxious stimuli. Cdk5, a member of the Cdk family, has recently been identified as a modulator of pain signaling pathways. In the current study, we investigated the extent to which Cdk5 modul...

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Veröffentlicht in:	Channels (Austin, Tex.) Tex.), 2018-01, Vol.12 (1), p.65-75
Hauptverfasser:	Sulak, Michael A, Ghosh, Monica, Sinharoy, Pritam, Andrei, Spencer R, Damron, Derek S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brief Report Cells, Cultured Cyclin-Dependent Kinase 5 - antagonists & inhibitors Cyclin-Dependent Kinase 5 - deficiency Cyclin-Dependent Kinase 5 - metabolism HEK293 Cells Humans Male Mice Mice, Inbred C57BL Mice, Knockout Phosphorylation - drug effects Sensory Receptor Cells - drug effects Sensory Receptor Cells - metabolism TRPA1 Cation Channel - antagonists & inhibitors TRPA1 Cation Channel - metabolism
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