Evaluation of meal replacements and a home food environment intervention for long-term weight loss: a randomized controlled trial
ABSTRACT Background Lifestyle change treatments for weight loss produce medically meaningful weight reductions, but lost weight is usually regained. Meal replacements (MRs) represent one avenue for improving long-term weight loss. Another, nutrition-focused approach involves having participants make...
Gespeichert in:
| Veröffentlicht in: | The American journal of clinical nutrition 2018-01, Vol.107 (1), p.12-19 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 19 |
|---|---|
| container_issue | 1 |
| container_start_page | 12 |
| container_title | The American journal of clinical nutrition |
| container_volume | 107 |
| creator | Lowe, Michael R Butryn, Meghan L Zhang, Fengqing |
| description | ABSTRACT
Background
Lifestyle change treatments for weight loss produce medically meaningful weight reductions, but lost weight is usually regained. Meal replacements (MRs) represent one avenue for improving long-term weight loss. Another, nutrition-focused approach involves having participants make specific changes in the energy density, composition, and structure of the foods in their personal food environments.
Objective
Three conditions were compared: behavior therapy (BT), BT plus MRs (BT+MR), and a nutrition-focused treatment aimed at modifying the home food environment (HFE).
Design
Overweight and obese individuals (n = 262) were randomly assigned to 1 of the 3 conditions. Treatment occurred in weekly groups for 6 mo and in biweekly groups for 6 mo. Assessments were conducted at baseline and at 6, 12, 18, 24, and 36 mo. Multilevel models were used to estimate weight-change trajectories for each participant and to examine the treatment group effect on long-term weight loss.
Results
A multilevel analysis indicated that all 3 groups showed significant weight loss over 12 mo that was gradually regained to the 36-mo follow-up. Mean ± SD percentages of baseline weight loss at 12 mo for BT, BT+MR, and HFE were 9.41% ± 7.92%, 10.37% ± 7.77%, and 10.97% ± 7.79%, respectively. Comparable percentages at 36 mo were 4.21% ± 8.64%, 3.06% ± 6.93%, and 4.49% ± 7.83%. Those in the HFE condition lost more weight than those receiving BT through the 36-mo assessment (P < 0.01), as reflected in 2 treatment × time interactions. Further analyses showed that HFE produced the largest increases in cognitive restraint and that this increase largely mediated the HFE group's improved weight loss.
Conclusion
The nutrition-focused intervention studied here produced modestly greater long-term weight loss than BT, an effect that was largely explainable by an unexpected boost in cognitive restraint in this condition. This study was registered at clinicaltrials.gov as NCT01065974. |
| doi_str_mv | 10.1093/ajcn/nqx005 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5972600</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><oup_id>10.1093/ajcn/nqx005</oup_id><sourcerecordid>2220910262</sourcerecordid><originalsourceid>FETCH-LOGICAL-c473t-efb4c22d4f3ee7ffa23bbadd1a85c52f5974d61a3abf0165c0c02a548047508a3</originalsourceid><addsrcrecordid>eNqFks9rFTEQx4NY7Gv15F0CQhFk7SSb_eWhIKVaoeBFz2E2m7yXRzZ5TXafP27-583yalEPesow85kvM5MvIc8ZvGHQlee4Vf7c334DqB6RFevKtig5NI_JCgB40bG6OiYnKW0BGBdt_YQc8wyxpmMr8vNqj27GyQZPg6GjRkej3jlUetR-ShT9QJFuwqipCWGg2u9tDH4pUusnHfc5WrpNiNQFvy5ybqRftV1vppxI6W3uj1kmjPaHHqgKforBuRxO0aJ7So4MuqSf3b-n5Mv7q8-X18XNpw8fL9_dFEo05VRo0wvF-SBMqXVjDPKy73EYGLaVqripukYMNcMSewN5ZQUKOFaiBdFU0GJ5Si4Ouru5H_Wg8tgRndxFO2L8LgNa-WfF241ch73MyrwGyAKv7gViuJ11muRok9LOoddhTpJzDh0DXvP_oqzrSoCmBpHRl3-h2zBHny8h-YI0INouU68PlIr5olGbh7kZyMUFcnGBPLgg0y9-X_WB_fXtGTg7AGHe_VPpDr8Wvyk</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2007670489</pqid></control><display><type>article</type><title>Evaluation of meal replacements and a home food environment intervention for long-term weight loss: a randomized controlled trial</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><creator>Lowe, Michael R ; Butryn, Meghan L ; Zhang, Fengqing</creator><creatorcontrib>Lowe, Michael R ; Butryn, Meghan L ; Zhang, Fengqing</creatorcontrib><description>ABSTRACT
Background
Lifestyle change treatments for weight loss produce medically meaningful weight reductions, but lost weight is usually regained. Meal replacements (MRs) represent one avenue for improving long-term weight loss. Another, nutrition-focused approach involves having participants make specific changes in the energy density, composition, and structure of the foods in their personal food environments.
Objective
Three conditions were compared: behavior therapy (BT), BT plus MRs (BT+MR), and a nutrition-focused treatment aimed at modifying the home food environment (HFE).
Design
Overweight and obese individuals (n = 262) were randomly assigned to 1 of the 3 conditions. Treatment occurred in weekly groups for 6 mo and in biweekly groups for 6 mo. Assessments were conducted at baseline and at 6, 12, 18, 24, and 36 mo. Multilevel models were used to estimate weight-change trajectories for each participant and to examine the treatment group effect on long-term weight loss.
Results
A multilevel analysis indicated that all 3 groups showed significant weight loss over 12 mo that was gradually regained to the 36-mo follow-up. Mean ± SD percentages of baseline weight loss at 12 mo for BT, BT+MR, and HFE were 9.41% ± 7.92%, 10.37% ± 7.77%, and 10.97% ± 7.79%, respectively. Comparable percentages at 36 mo were 4.21% ± 8.64%, 3.06% ± 6.93%, and 4.49% ± 7.83%. Those in the HFE condition lost more weight than those receiving BT through the 36-mo assessment (P < 0.01), as reflected in 2 treatment × time interactions. Further analyses showed that HFE produced the largest increases in cognitive restraint and that this increase largely mediated the HFE group's improved weight loss.
Conclusion
The nutrition-focused intervention studied here produced modestly greater long-term weight loss than BT, an effect that was largely explainable by an unexpected boost in cognitive restraint in this condition. This study was registered at clinicaltrials.gov as NCT01065974.</description><identifier>ISSN: 0002-9165</identifier><identifier>ISSN: 1938-3207</identifier><identifier>EISSN: 1938-3207</identifier><identifier>DOI: 10.1093/ajcn/nqx005</identifier><identifier>PMID: 29381791</identifier><language>eng</language><publisher>United States: Oxford University Press</publisher><subject>Adolescent ; Adult ; Aged ; behavior modification ; Behavior therapy ; Body Mass Index ; Body weight ; Body weight loss ; Clinical trials ; cognition ; Cognitive ability ; Design modifications ; Diet ; energy density ; Exercise ; Female ; Flux density ; Follow-Up Studies ; Food ; foods ; group effect ; Health Behavior ; Home meal replacement ; Houses ; Humans ; Intervention ; Life Style ; lifestyle ; Male ; Meals ; Middle Aged ; Nutrition ; Obesity - therapy ; Original Research Communications ; Overweight ; Overweight - therapy ; randomized clinical trials ; Surveys and Questionnaires ; Trajectory analysis ; Treatment Outcome ; Weight control ; Weight Loss ; Weight reduction ; Young Adult</subject><ispartof>The American journal of clinical nutrition, 2018-01, Vol.107 (1), p.12-19</ispartof><rights>2018 American Society for Nutrition. All rights reserved. 2018</rights><rights>2018 American Society for Nutrition. All rights reserved.</rights><rights>Copyright American Society for Clinical Nutrition, Inc. Jan 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c473t-efb4c22d4f3ee7ffa23bbadd1a85c52f5974d61a3abf0165c0c02a548047508a3</citedby><cites>FETCH-LOGICAL-c473t-efb4c22d4f3ee7ffa23bbadd1a85c52f5974d61a3abf0165c0c02a548047508a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29381791$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lowe, Michael R</creatorcontrib><creatorcontrib>Butryn, Meghan L</creatorcontrib><creatorcontrib>Zhang, Fengqing</creatorcontrib><title>Evaluation of meal replacements and a home food environment intervention for long-term weight loss: a randomized controlled trial</title><title>The American journal of clinical nutrition</title><addtitle>Am J Clin Nutr</addtitle><description>ABSTRACT
Background
Lifestyle change treatments for weight loss produce medically meaningful weight reductions, but lost weight is usually regained. Meal replacements (MRs) represent one avenue for improving long-term weight loss. Another, nutrition-focused approach involves having participants make specific changes in the energy density, composition, and structure of the foods in their personal food environments.
Objective
Three conditions were compared: behavior therapy (BT), BT plus MRs (BT+MR), and a nutrition-focused treatment aimed at modifying the home food environment (HFE).
Design
Overweight and obese individuals (n = 262) were randomly assigned to 1 of the 3 conditions. Treatment occurred in weekly groups for 6 mo and in biweekly groups for 6 mo. Assessments were conducted at baseline and at 6, 12, 18, 24, and 36 mo. Multilevel models were used to estimate weight-change trajectories for each participant and to examine the treatment group effect on long-term weight loss.
Results
A multilevel analysis indicated that all 3 groups showed significant weight loss over 12 mo that was gradually regained to the 36-mo follow-up. Mean ± SD percentages of baseline weight loss at 12 mo for BT, BT+MR, and HFE were 9.41% ± 7.92%, 10.37% ± 7.77%, and 10.97% ± 7.79%, respectively. Comparable percentages at 36 mo were 4.21% ± 8.64%, 3.06% ± 6.93%, and 4.49% ± 7.83%. Those in the HFE condition lost more weight than those receiving BT through the 36-mo assessment (P < 0.01), as reflected in 2 treatment × time interactions. Further analyses showed that HFE produced the largest increases in cognitive restraint and that this increase largely mediated the HFE group's improved weight loss.
Conclusion
The nutrition-focused intervention studied here produced modestly greater long-term weight loss than BT, an effect that was largely explainable by an unexpected boost in cognitive restraint in this condition. This study was registered at clinicaltrials.gov as NCT01065974.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>behavior modification</subject><subject>Behavior therapy</subject><subject>Body Mass Index</subject><subject>Body weight</subject><subject>Body weight loss</subject><subject>Clinical trials</subject><subject>cognition</subject><subject>Cognitive ability</subject><subject>Design modifications</subject><subject>Diet</subject><subject>energy density</subject><subject>Exercise</subject><subject>Female</subject><subject>Flux density</subject><subject>Follow-Up Studies</subject><subject>Food</subject><subject>foods</subject><subject>group effect</subject><subject>Health Behavior</subject><subject>Home meal replacement</subject><subject>Houses</subject><subject>Humans</subject><subject>Intervention</subject><subject>Life Style</subject><subject>lifestyle</subject><subject>Male</subject><subject>Meals</subject><subject>Middle Aged</subject><subject>Nutrition</subject><subject>Obesity - therapy</subject><subject>Original Research Communications</subject><subject>Overweight</subject><subject>Overweight - therapy</subject><subject>randomized clinical trials</subject><subject>Surveys and Questionnaires</subject><subject>Trajectory analysis</subject><subject>Treatment Outcome</subject><subject>Weight control</subject><subject>Weight Loss</subject><subject>Weight reduction</subject><subject>Young Adult</subject><issn>0002-9165</issn><issn>1938-3207</issn><issn>1938-3207</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFks9rFTEQx4NY7Gv15F0CQhFk7SSb_eWhIKVaoeBFz2E2m7yXRzZ5TXafP27-583yalEPesow85kvM5MvIc8ZvGHQlee4Vf7c334DqB6RFevKtig5NI_JCgB40bG6OiYnKW0BGBdt_YQc8wyxpmMr8vNqj27GyQZPg6GjRkej3jlUetR-ShT9QJFuwqipCWGg2u9tDH4pUusnHfc5WrpNiNQFvy5ybqRftV1vppxI6W3uj1kmjPaHHqgKforBuRxO0aJ7So4MuqSf3b-n5Mv7q8-X18XNpw8fL9_dFEo05VRo0wvF-SBMqXVjDPKy73EYGLaVqripukYMNcMSewN5ZQUKOFaiBdFU0GJ5Si4Ouru5H_Wg8tgRndxFO2L8LgNa-WfF241ch73MyrwGyAKv7gViuJ11muRok9LOoddhTpJzDh0DXvP_oqzrSoCmBpHRl3-h2zBHny8h-YI0INouU68PlIr5olGbh7kZyMUFcnGBPLgg0y9-X_WB_fXtGTg7AGHe_VPpDr8Wvyk</recordid><startdate>20180101</startdate><enddate>20180101</enddate><creator>Lowe, Michael R</creator><creator>Butryn, Meghan L</creator><creator>Zhang, Fengqing</creator><general>Oxford University Press</general><general>American Society for Clinical Nutrition, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7T7</scope><scope>7TS</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope><scope>7S9</scope><scope>L.6</scope><scope>5PM</scope></search><sort><creationdate>20180101</creationdate><title>Evaluation of meal replacements and a home food environment intervention for long-term weight loss: a randomized controlled trial</title><author>Lowe, Michael R ; Butryn, Meghan L ; Zhang, Fengqing</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c473t-efb4c22d4f3ee7ffa23bbadd1a85c52f5974d61a3abf0165c0c02a548047508a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>behavior modification</topic><topic>Behavior therapy</topic><topic>Body Mass Index</topic><topic>Body weight</topic><topic>Body weight loss</topic><topic>Clinical trials</topic><topic>cognition</topic><topic>Cognitive ability</topic><topic>Design modifications</topic><topic>Diet</topic><topic>energy density</topic><topic>Exercise</topic><topic>Female</topic><topic>Flux density</topic><topic>Follow-Up Studies</topic><topic>Food</topic><topic>foods</topic><topic>group effect</topic><topic>Health Behavior</topic><topic>Home meal replacement</topic><topic>Houses</topic><topic>Humans</topic><topic>Intervention</topic><topic>Life Style</topic><topic>lifestyle</topic><topic>Male</topic><topic>Meals</topic><topic>Middle Aged</topic><topic>Nutrition</topic><topic>Obesity - therapy</topic><topic>Original Research Communications</topic><topic>Overweight</topic><topic>Overweight - therapy</topic><topic>randomized clinical trials</topic><topic>Surveys and Questionnaires</topic><topic>Trajectory analysis</topic><topic>Treatment Outcome</topic><topic>Weight control</topic><topic>Weight Loss</topic><topic>Weight reduction</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lowe, Michael R</creatorcontrib><creatorcontrib>Butryn, Meghan L</creatorcontrib><creatorcontrib>Zhang, Fengqing</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Physical Education Index</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The American journal of clinical nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lowe, Michael R</au><au>Butryn, Meghan L</au><au>Zhang, Fengqing</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of meal replacements and a home food environment intervention for long-term weight loss: a randomized controlled trial</atitle><jtitle>The American journal of clinical nutrition</jtitle><addtitle>Am J Clin Nutr</addtitle><date>2018-01-01</date><risdate>2018</risdate><volume>107</volume><issue>1</issue><spage>12</spage><epage>19</epage><pages>12-19</pages><issn>0002-9165</issn><issn>1938-3207</issn><eissn>1938-3207</eissn><abstract>ABSTRACT
Background
Lifestyle change treatments for weight loss produce medically meaningful weight reductions, but lost weight is usually regained. Meal replacements (MRs) represent one avenue for improving long-term weight loss. Another, nutrition-focused approach involves having participants make specific changes in the energy density, composition, and structure of the foods in their personal food environments.
Objective
Three conditions were compared: behavior therapy (BT), BT plus MRs (BT+MR), and a nutrition-focused treatment aimed at modifying the home food environment (HFE).
Design
Overweight and obese individuals (n = 262) were randomly assigned to 1 of the 3 conditions. Treatment occurred in weekly groups for 6 mo and in biweekly groups for 6 mo. Assessments were conducted at baseline and at 6, 12, 18, 24, and 36 mo. Multilevel models were used to estimate weight-change trajectories for each participant and to examine the treatment group effect on long-term weight loss.
Results
A multilevel analysis indicated that all 3 groups showed significant weight loss over 12 mo that was gradually regained to the 36-mo follow-up. Mean ± SD percentages of baseline weight loss at 12 mo for BT, BT+MR, and HFE were 9.41% ± 7.92%, 10.37% ± 7.77%, and 10.97% ± 7.79%, respectively. Comparable percentages at 36 mo were 4.21% ± 8.64%, 3.06% ± 6.93%, and 4.49% ± 7.83%. Those in the HFE condition lost more weight than those receiving BT through the 36-mo assessment (P < 0.01), as reflected in 2 treatment × time interactions. Further analyses showed that HFE produced the largest increases in cognitive restraint and that this increase largely mediated the HFE group's improved weight loss.
Conclusion
The nutrition-focused intervention studied here produced modestly greater long-term weight loss than BT, an effect that was largely explainable by an unexpected boost in cognitive restraint in this condition. This study was registered at clinicaltrials.gov as NCT01065974.</abstract><cop>United States</cop><pub>Oxford University Press</pub><pmid>29381791</pmid><doi>10.1093/ajcn/nqx005</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-9165 |
| ispartof | The American journal of clinical nutrition, 2018-01, Vol.107 (1), p.12-19 |
| issn | 0002-9165 1938-3207 1938-3207 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5972600 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Adolescent Adult Aged behavior modification Behavior therapy Body Mass Index Body weight Body weight loss Clinical trials cognition Cognitive ability Design modifications Diet energy density Exercise Female Flux density Follow-Up Studies Food foods group effect Health Behavior Home meal replacement Houses Humans Intervention Life Style lifestyle Male Meals Middle Aged Nutrition Obesity - therapy Original Research Communications Overweight Overweight - therapy randomized clinical trials Surveys and Questionnaires Trajectory analysis Treatment Outcome Weight control Weight Loss Weight reduction Young Adult |
| title | Evaluation of meal replacements and a home food environment intervention for long-term weight loss: a randomized controlled trial |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-08T00%3A47%3A49IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Evaluation%20of%20meal%20replacements%20and%20a%20home%20food%20environment%20intervention%20for%20long-term%20weight%20loss:%20a%20randomized%20controlled%20trial&rft.jtitle=The%20American%20journal%20of%20clinical%20nutrition&rft.au=Lowe,%20Michael%20R&rft.date=2018-01-01&rft.volume=107&rft.issue=1&rft.spage=12&rft.epage=19&rft.pages=12-19&rft.issn=0002-9165&rft.eissn=1938-3207&rft_id=info:doi/10.1093/ajcn/nqx005&rft_dat=%3Cproquest_pubme%3E2220910262%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2007670489&rft_id=info:pmid/29381791&rft_oup_id=10.1093/ajcn/nqx005&rfr_iscdi=true |