Genetic Determinants of High-Level Oxacillin Resistance in Methicillin-Resistant Staphylococcus aureus

Methicillin-resistant (MRSA) strains carry either a - or a -mediated mechanism of resistance to beta-lactam antibiotics, and the phenotypic expression of resistance shows extensive strain-to-strain variation. In recent communications, we identified the genetic determinants associated with the string...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2018-06, Vol.62 (6), p.e00206-18
Hauptverfasser:	Pardos de la Gandara, Maria, Borges, Vitor, Chung, Marilyn, Milheiriço, Catarina, Gomes, João Paulo, de Lencastre, Herminia, Tomasz, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents Anti-Bacterial Agents - pharmacology Bacterial Proteins Bacterial Proteins - genetics Bacteriology Biochemistry, Molecular Biology Denmark Genomics Guanine Guanine - metabolism Humans Life Sciences Mechanisms of Resistance Methicillin Resistance Methicillin Resistance - genetics Methicillin-Resistant Staphylococcus aureus Methicillin-Resistant Staphylococcus aureus - drug effects Methicillin-Resistant Staphylococcus aureus - genetics Methicillin-Resistant Staphylococcus aureus - isolation & purification Microbial Sensitivity Tests Microbiology and Parasitology Molecular biology Oxacillin Oxacillin - pharmacology Penicillin-Binding Proteins Penicillin-Binding Proteins - genetics United Kingdom Whole Genome Sequencing
Online-Zugang:	Volltext
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