One Intact Transmembrane Substrate Binding Site Is Sufficient for the Function of the Homodimeric Type I ATP-Binding Cassette Importer for Positively Charged Amino Acids Art(MP) 2 of Geobacillus stearothermophilus

ATP-binding cassette (ABC) transport systems comprise two transmembrane domains/subunits that form a translocation path and two nucleotide-binding domains/subunits that bind and hydrolyze ATP. Prokaryotic canonical ABC import systems require an extracellular substrate-binding protein for function. K...

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Veröffentlicht in:	Journal of bacteriology 2018-06, Vol.200 (12)
Hauptverfasser:	Heuveling, Johanna, Landmesser, Heidi, Schneider, Erwin
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Motifs Amino Acids, Basic - metabolism ATP-Binding Cassette Transporters - chemistry ATP-Binding Cassette Transporters - genetics ATP-Binding Cassette Transporters - metabolism Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - metabolism Binding Sites Dimerization Geobacillus stearothermophilus - chemistry Geobacillus stearothermophilus - genetics Geobacillus stearothermophilus - metabolism
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