Cryo-EM structure of the exocyst complex

The exocyst is an evolutionarily conserved octameric protein complex that mediates the tethering of post-Golgi secretory vesicles to the plasma membrane during exocytosis and is implicated in many cellular processes such as cell polarization, cytokinesis, ciliogenesis and tumor invasion. Using cryo-...

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Veröffentlicht in:	Nature structural & molecular biology 2018-02, Vol.25 (2), p.139-146
Hauptverfasser:	Mei, Kunrong, Li, Yan, Wang, Shaoxiao, Shao, Guangcan, Wang, Jia, Ding, Yuehe, Luo, Guangzuo, Yue, Peng, Liu, Jun-Jie, Wang, Xinquan, Dong, Meng-Qiu, Wang, Hong-Wei, Guo, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	101/28 101/58 13 13/1 13/44 14/19 14/28 14/32 14/35 631/45/535/1258/1259 631/80/313/1481 Amino Acid Motifs Assembly Biochemistry Biological Microscopy Biological research Biological Transport Biomedical and Life Sciences Cell Membrane - metabolism Cell membranes Chromatography Conserved sequence Cross-Linking Reagents Crosslinking Cryoelectron Microscopy - methods Crystallography Cytokinesis Cytoplasm - metabolism Exocytosis Fungi Golgi apparatus Golgi Apparatus - metabolism Image Processing, Computer-Assisted Laboratories Life Sciences Mass Spectrometry Membrane Biology Membrane vesicles Molecular biology Organelles Organic chemistry Physiological aspects Protein Binding Protein Multimerization Protein Structure Proteins Saccharomyces cerevisiae Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - metabolism Secretory vesicles Secretory Vesicles - metabolism Tethering Tumors Vesicular Transport Proteins - metabolism
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