QSAR analysis of substituent effects on tambjamine anion transporters† ‡ †Electronic supplementary information (ESI) available: Synthesis of new compounds, anion transport studies and details of the QSAR analysis. See DOI: 10.1039/c5sc03932k ‡The underlying research data for this paper are available in accordance with EPSRC open data policy from http://dx.doi.org/10.5258/SOTON/384138

A QSAR analysis of the transmembrane anion transport activity of 43 synthetic tambjamine analogs allowed rationalization of this activity according to their lipophilicity and structural parameters. The transmembrane anion transport activity of 43 synthetic molecules based on the structure of marine...

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Veröffentlicht in:Chemical science (Cambridge) 2015-12, Vol.7 (2), p.1600-1608
Hauptverfasser: Knight, Nicola J., Hernando, Elsa, Haynes, Cally J. E., Busschaert, Nathalie, Clarke, Harriet J., Takimoto, Koji, García-Valverde, María, Frey, Jeremy G., Quesada, Roberto, Gale, Philip A.
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