Conserved and divergent functions of Pax6 underlie species-specific neurogenic patterns in the developing amniote brain

The evolution of unique organ structures is associated with changes in conserved developmental programs. However, characterizing the functional conservation and variation of homologous transcription factors (TFs) that dictate species-specific cellular dynamics has remained elusive. Here, we dissect...

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Veröffentlicht in:	Development (Cambridge) 2018-04, Vol.145 (8), p.dev159764-dev159764
Hauptverfasser:	Yamashita, Wataru, Takahashi, Masanori, Kikkawa, Takako, Gotoh, Hitoshi, Osumi, Noriko, Ono, Katsuhiko, Nomura, Tadashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Dbx1 protein Developmental stages Divergence Mammals Neocortex Neural stem cells Neurogenesis Notch protein Pallium Pax6 protein Retinal ganglion cells Species Telencephalon Transcription factors
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