Metal homeostasis and resistance in bacteria

Key Points Specific protein-based and riboswitch-based metal sensors monitor the intracellular levels of metal ions and regulate the expression of pathways for uptake, storage and efflux, as well as alternative enzymes that use a different metal or non-metal cofactor. Transcription factors often med...

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Veröffentlicht in:	Nature reviews. Microbiology 2017-06, Vol.15 (6), p.338-350
Hauptverfasser:	Chandrangsu, Pete, Rensing, Christopher, Helmann, John D.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/326 631/326/1320 631/326/41/1969 631/326/41/88 631/45/612/1141 631/45/612/822 Bacillus subtilis - genetics Bacillus subtilis - metabolism Bacteria Bacterial infections Bacterial Proteins - metabolism Cofactors Development and progression Efflux Genetic aspects Health aspects Historical metallurgy Homeostasis Infectious Diseases Intoxication Iron - metabolism Life Sciences Manganese - metabolism Medical Microbiology Membrane Proteins - metabolism Metal ions Metals Microbiology Parasitology Post-transcription Properties Repressor Proteins - metabolism review-article Ribonucleic acid Riboswitch - genetics RNA Transcription Virology Zinc - metabolism
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