Highly Bactericidal Macroporous Antimicrobial Polymeric Gel for Point-of-Use Water Disinfection

Access to clean and safe water supply remains inadequate in many developing countries. One of the key challenges is to remove pathogenic bacteria from the water supply via effective water disinfection technologies to prevent the spread of diseases and to ensure the safety of consumers. Herein, a hig...

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Veröffentlicht in:Scientific reports 2018-05, Vol.8 (1), p.7965-9, Article 7965
Hauptverfasser: Kumar, Amit, Boyer, Cyrille, Nebhani, Leena, Wong, Edgar H. H.
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creator Kumar, Amit
Boyer, Cyrille
Nebhani, Leena
Wong, Edgar H. H.
description Access to clean and safe water supply remains inadequate in many developing countries. One of the key challenges is to remove pathogenic bacteria from the water supply via effective water disinfection technologies to prevent the spread of diseases and to ensure the safety of consumers. Herein, a highly effective point-of-use (on-demand) water disinfection technology, in the form of a polymeric scaffold called macroporous antimicrobial polymeric gel (MAPG), is demonstrated. MAPG is easy to fabricate, completely organic and possess inherent antimicrobial property which makes it non-reliant on inorganic compounds such as silver where the long-term toxicity remains unknown. MAPG is highly bactericidal and can disinfect bacteria-contaminated water (ca. 10 8  CFU mL −1 ) at a capacity of about >50 times the mass of the organic material used, inactivating >99% of both Gram-negative and Gram-positive bacteria including Escherichia coli , Vibrio cholerae and Staphylococcus aureus within 20 minutes of treatment. When fabricated in a syringe, MAPG eliminates E. coli from contaminated water source by >8.0 log 10 reduction in bacteria counts (i.e., no viable bacteria were detected after treatment), and the syringe can be reused multiple times without losing potency. The MAPG technology is not only restricted to water disinfection but may also be applicable in other bacteria inactivation applications.
doi_str_mv 10.1038/s41598-018-26202-0
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subjects 13/106
140/131
639/301/923/1028
639/638/298/923/1027
Anti-Bacterial Agents - pharmacology
Antimicrobial agents
Bacteria
Bacteria - drug effects
Developing countries
Disinfectants - pharmacology
Disinfection
Escherichia coli
Gels
Gram-positive bacteria
Humanities and Social Sciences
Inorganic compounds
LDCs
multidisciplinary
Point-of-Care Testing - statistics & numerical data
Polymers - pharmacology
Science
Science (multidisciplinary)
Toxicity
Water Microbiology
Water Purification - methods
Water shortages
Water supply
title Highly Bactericidal Macroporous Antimicrobial Polymeric Gel for Point-of-Use Water Disinfection
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