Impact of extracorporeal cardiopulmonary resuscitation on outcomes of elderly patients who had out-of-hospital cardiac arrests: a single-centre retrospective analysis
ObjectivesLittle is known about the effectiveness of extracorporeal cardiopulmonary resuscitation (ECPR) for elderly patients who had out-of-hospital cardiac arrest (OHCA). The aim of this study was to examine the impact of age on outcomes among patients who had OHCA treated with ECPR.DesignSingle-c...
Gespeichert in:
| Veröffentlicht in: | BMJ open 2018-05, Vol.8 (5), p.e019811-e019811 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e019811 |
|---|---|
| container_issue | 5 |
| container_start_page | e019811 |
| container_title | BMJ open |
| container_volume | 8 |
| creator | Goto, Tadahiro Morita, Sachiko Kitamura, Tetsuhisa Natsukawa, Tomoaki Sawano, Hirotaka Hayashi, Yasuyuki Kai, Tatsuro |
| description | ObjectivesLittle is known about the effectiveness of extracorporeal cardiopulmonary resuscitation (ECPR) for elderly patients who had out-of-hospital cardiac arrest (OHCA). The aim of this study was to examine the impact of age on outcomes among patients who had OHCA treated with ECPR.DesignSingle-centre retrospective cohort study.SettingA critical care centre that covers a population of approximately 1 million residents.ParticipantsPatients who had consecutive OHCA aged ≥18 years who underwent ECPR from 2005 to 2013.Primary and secondary outcome measuresPrimary outcomes were 1 month neurologically favourable outcomes and survival. To determine the association between advanced age and each outcome, we fitted multivariable logistic regression models using: (1) age as a continuous variable and (2) age as a categorical variable ( |
| doi_str_mv | 10.1136/bmjopen-2017-019811 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5961566</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2099496447</sourcerecordid><originalsourceid>FETCH-LOGICAL-b516t-33b8c31c97c0b7a48c8388810c78fdfb53243e226c805f2a73c198d8fbb1c383</originalsourceid><addsrcrecordid>eNqNkk1rHSEUhqW0JCHNLwgUoZtuJvV7tItCCf0IBLLJXhzHyfXijFN10tw_1N9ZJ_c2pF1FBIXzvK_nHA8A5xhdYEzFx27cxtlNDUG4bRBWEuNX4IQgxhqBOH_97H4MznLeoroYV5yTI3BMlGqlRPIE_L4aZ2MLjAN0DyUZG9MckzMBWpN6H-cljHEyaQeTy0u2vpji4wTXvRQbR5cftaF3KezgXKNuKhn-2kS4Mf0KNXFoNjHPVXpwNRaaVP1K_gQNzH66C66xVZdcfaakCjtb_L2DZjJhl31-C94MJmR3djhPwe23r7eXP5rrm-9Xl1-um45jURpKO2kptqq1qGsNk1ZSKSVGtpVDP3ScEkYdIcJKxAdiWmpr63o5dB22VNJT8HlvOy_d6PrHlEzQc_JjbYGOxut_I5Pf6Lt4r7kSmAtRDT4cDFL8udQK9eizdSGYycUla4KEYK3ijFT0_X_oNi6p1rtSSjElGGsrRfeUrV3JyQ1PyWCk10nQh0nQ6yTo_SRU1bvndTxp_v57BS72QFW_yPEPodTFPA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2099496447</pqid></control><display><type>article</type><title>Impact of extracorporeal cardiopulmonary resuscitation on outcomes of elderly patients who had out-of-hospital cardiac arrests: a single-centre retrospective analysis</title><source>BMJ Open Access Journals</source><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>PubMed Central Open Access</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Goto, Tadahiro ; Morita, Sachiko ; Kitamura, Tetsuhisa ; Natsukawa, Tomoaki ; Sawano, Hirotaka ; Hayashi, Yasuyuki ; Kai, Tatsuro</creator><creatorcontrib>Goto, Tadahiro ; Morita, Sachiko ; Kitamura, Tetsuhisa ; Natsukawa, Tomoaki ; Sawano, Hirotaka ; Hayashi, Yasuyuki ; Kai, Tatsuro</creatorcontrib><description>ObjectivesLittle is known about the effectiveness of extracorporeal cardiopulmonary resuscitation (ECPR) for elderly patients who had out-of-hospital cardiac arrest (OHCA). The aim of this study was to examine the impact of age on outcomes among patients who had OHCA treated with ECPR.DesignSingle-centre retrospective cohort study.SettingA critical care centre that covers a population of approximately 1 million residents.ParticipantsPatients who had consecutive OHCA aged ≥18 years who underwent ECPR from 2005 to 2013.Primary and secondary outcome measuresPrimary outcomes were 1 month neurologically favourable outcomes and survival. To determine the association between advanced age and each outcome, we fitted multivariable logistic regression models using: (1) age as a continuous variable and (2) age as a categorical variable (<50 years, 50–59 years, 60–69 years and ≥70 years).ResultsOverall, 144 patients who had OHCA who underwent ECPR were eligible for our analyses. The proportion of neurologically favourable outcomes was 7%, while survival was 19% in patients who had OHCA. After the adjustment for potential confounders, while advanced age was non-significantly associated with neurologically favourable outcomes (adjusted OR 0.96 (95% CI 0.91 to 1.01), p=0.08), the association between advanced age and the poor survival rate was significant (adjusted OR 0.96 (95% CI 0.93 to 0.99), p=0.04). Additionally, compared with age <50 years, age ≥70 years was non-significantly associated with poor neurological outcomes (adjusted OR 0.08 (95% CI 0.01 to 1.00), p=0.051), whereas age ≥70 years was significantly associated with worse survival in the adjusted model (adjusted OR 0.14 (95% CI 0.03 to 0.80), p=0.03).ConclusionsIn our analysis of consecutive OHCA data from a critical care hospital in an urban area of Japan, we found that advanced age was associated with the lower rate of 1-month survival in patients who had OHCA who underwent ECPR. Although larger studies are required to confirm these results, our findings suggest that ECPR may not be beneficial for patients who had OHCA aged ≥70 years.</description><identifier>ISSN: 2044-6055</identifier><identifier>EISSN: 2044-6055</identifier><identifier>DOI: 10.1136/bmjopen-2017-019811</identifier><identifier>PMID: 29978808</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>Age ; Age Factors ; Aged ; Ambulance services ; Cardiac arrest ; Cardiac arrhythmia ; Cardiopulmonary resuscitation ; Cardiopulmonary Resuscitation - mortality ; Chronic obstructive pulmonary disease ; Clinical Decision-Making ; CPR ; Critical care ; Emergency Medicine ; Extracorporeal membrane oxygenation ; Extracorporeal Membrane Oxygenation - mortality ; Female ; Heart attacks ; Hospitals ; Humans ; Japan ; Logistic Models ; Male ; Medical prognosis ; Medical records ; Middle Aged ; Older people ; Out-of-Hospital Cardiac Arrest - mortality ; Out-of-Hospital Cardiac Arrest - therapy ; Patients ; Physicians ; Retrospective Studies ; Systematic review</subject><ispartof>BMJ open, 2018-05, Vol.8 (5), p.e019811-e019811</ispartof><rights>Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.</rights><rights>2018 Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b516t-33b8c31c97c0b7a48c8388810c78fdfb53243e226c805f2a73c198d8fbb1c383</citedby><cites>FETCH-LOGICAL-b516t-33b8c31c97c0b7a48c8388810c78fdfb53243e226c805f2a73c198d8fbb1c383</cites><orcidid>0000-0002-5880-2968</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://bmjopen.bmj.com/content/8/5/e019811.full.pdf$$EPDF$$P50$$Gbmj$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://bmjopen.bmj.com/content/8/5/e019811.full$$EHTML$$P50$$Gbmj$$Hfree_for_read</linktohtml><link.rule.ids>230,314,725,778,782,862,883,27532,27533,27907,27908,53774,53776,77352,77383</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29978808$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Goto, Tadahiro</creatorcontrib><creatorcontrib>Morita, Sachiko</creatorcontrib><creatorcontrib>Kitamura, Tetsuhisa</creatorcontrib><creatorcontrib>Natsukawa, Tomoaki</creatorcontrib><creatorcontrib>Sawano, Hirotaka</creatorcontrib><creatorcontrib>Hayashi, Yasuyuki</creatorcontrib><creatorcontrib>Kai, Tatsuro</creatorcontrib><title>Impact of extracorporeal cardiopulmonary resuscitation on outcomes of elderly patients who had out-of-hospital cardiac arrests: a single-centre retrospective analysis</title><title>BMJ open</title><addtitle>BMJ Open</addtitle><description>ObjectivesLittle is known about the effectiveness of extracorporeal cardiopulmonary resuscitation (ECPR) for elderly patients who had out-of-hospital cardiac arrest (OHCA). The aim of this study was to examine the impact of age on outcomes among patients who had OHCA treated with ECPR.DesignSingle-centre retrospective cohort study.SettingA critical care centre that covers a population of approximately 1 million residents.ParticipantsPatients who had consecutive OHCA aged ≥18 years who underwent ECPR from 2005 to 2013.Primary and secondary outcome measuresPrimary outcomes were 1 month neurologically favourable outcomes and survival. To determine the association between advanced age and each outcome, we fitted multivariable logistic regression models using: (1) age as a continuous variable and (2) age as a categorical variable (<50 years, 50–59 years, 60–69 years and ≥70 years).ResultsOverall, 144 patients who had OHCA who underwent ECPR were eligible for our analyses. The proportion of neurologically favourable outcomes was 7%, while survival was 19% in patients who had OHCA. After the adjustment for potential confounders, while advanced age was non-significantly associated with neurologically favourable outcomes (adjusted OR 0.96 (95% CI 0.91 to 1.01), p=0.08), the association between advanced age and the poor survival rate was significant (adjusted OR 0.96 (95% CI 0.93 to 0.99), p=0.04). Additionally, compared with age <50 years, age ≥70 years was non-significantly associated with poor neurological outcomes (adjusted OR 0.08 (95% CI 0.01 to 1.00), p=0.051), whereas age ≥70 years was significantly associated with worse survival in the adjusted model (adjusted OR 0.14 (95% CI 0.03 to 0.80), p=0.03).ConclusionsIn our analysis of consecutive OHCA data from a critical care hospital in an urban area of Japan, we found that advanced age was associated with the lower rate of 1-month survival in patients who had OHCA who underwent ECPR. Although larger studies are required to confirm these results, our findings suggest that ECPR may not be beneficial for patients who had OHCA aged ≥70 years.</description><subject>Age</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Ambulance services</subject><subject>Cardiac arrest</subject><subject>Cardiac arrhythmia</subject><subject>Cardiopulmonary resuscitation</subject><subject>Cardiopulmonary Resuscitation - mortality</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Clinical Decision-Making</subject><subject>CPR</subject><subject>Critical care</subject><subject>Emergency Medicine</subject><subject>Extracorporeal membrane oxygenation</subject><subject>Extracorporeal Membrane Oxygenation - mortality</subject><subject>Female</subject><subject>Heart attacks</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Japan</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Medical prognosis</subject><subject>Medical records</subject><subject>Middle Aged</subject><subject>Older people</subject><subject>Out-of-Hospital Cardiac Arrest - mortality</subject><subject>Out-of-Hospital Cardiac Arrest - therapy</subject><subject>Patients</subject><subject>Physicians</subject><subject>Retrospective Studies</subject><subject>Systematic review</subject><issn>2044-6055</issn><issn>2044-6055</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>9YT</sourceid><sourceid>ACMMV</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNkk1rHSEUhqW0JCHNLwgUoZtuJvV7tItCCf0IBLLJXhzHyfXijFN10tw_1N9ZJ_c2pF1FBIXzvK_nHA8A5xhdYEzFx27cxtlNDUG4bRBWEuNX4IQgxhqBOH_97H4MznLeoroYV5yTI3BMlGqlRPIE_L4aZ2MLjAN0DyUZG9MckzMBWpN6H-cljHEyaQeTy0u2vpji4wTXvRQbR5cftaF3KezgXKNuKhn-2kS4Mf0KNXFoNjHPVXpwNRaaVP1K_gQNzH66C66xVZdcfaakCjtb_L2DZjJhl31-C94MJmR3djhPwe23r7eXP5rrm-9Xl1-um45jURpKO2kptqq1qGsNk1ZSKSVGtpVDP3ScEkYdIcJKxAdiWmpr63o5dB22VNJT8HlvOy_d6PrHlEzQc_JjbYGOxut_I5Pf6Lt4r7kSmAtRDT4cDFL8udQK9eizdSGYycUla4KEYK3ijFT0_X_oNi6p1rtSSjElGGsrRfeUrV3JyQ1PyWCk10nQh0nQ6yTo_SRU1bvndTxp_v57BS72QFW_yPEPodTFPA</recordid><startdate>20180518</startdate><enddate>20180518</enddate><creator>Goto, Tadahiro</creator><creator>Morita, Sachiko</creator><creator>Kitamura, Tetsuhisa</creator><creator>Natsukawa, Tomoaki</creator><creator>Sawano, Hirotaka</creator><creator>Hayashi, Yasuyuki</creator><creator>Kai, Tatsuro</creator><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>9YT</scope><scope>ACMMV</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-5880-2968</orcidid></search><sort><creationdate>20180518</creationdate><title>Impact of extracorporeal cardiopulmonary resuscitation on outcomes of elderly patients who had out-of-hospital cardiac arrests: a single-centre retrospective analysis</title><author>Goto, Tadahiro ; Morita, Sachiko ; Kitamura, Tetsuhisa ; Natsukawa, Tomoaki ; Sawano, Hirotaka ; Hayashi, Yasuyuki ; Kai, Tatsuro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b516t-33b8c31c97c0b7a48c8388810c78fdfb53243e226c805f2a73c198d8fbb1c383</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Age</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Ambulance services</topic><topic>Cardiac arrest</topic><topic>Cardiac arrhythmia</topic><topic>Cardiopulmonary resuscitation</topic><topic>Cardiopulmonary Resuscitation - mortality</topic><topic>Chronic obstructive pulmonary disease</topic><topic>Clinical Decision-Making</topic><topic>CPR</topic><topic>Critical care</topic><topic>Emergency Medicine</topic><topic>Extracorporeal membrane oxygenation</topic><topic>Extracorporeal Membrane Oxygenation - mortality</topic><topic>Female</topic><topic>Heart attacks</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Japan</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Medical prognosis</topic><topic>Medical records</topic><topic>Middle Aged</topic><topic>Older people</topic><topic>Out-of-Hospital Cardiac Arrest - mortality</topic><topic>Out-of-Hospital Cardiac Arrest - therapy</topic><topic>Patients</topic><topic>Physicians</topic><topic>Retrospective Studies</topic><topic>Systematic review</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Goto, Tadahiro</creatorcontrib><creatorcontrib>Morita, Sachiko</creatorcontrib><creatorcontrib>Kitamura, Tetsuhisa</creatorcontrib><creatorcontrib>Natsukawa, Tomoaki</creatorcontrib><creatorcontrib>Sawano, Hirotaka</creatorcontrib><creatorcontrib>Hayashi, Yasuyuki</creatorcontrib><creatorcontrib>Kai, Tatsuro</creatorcontrib><collection>BMJ Open Access Journals</collection><collection>BMJ Journals:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMJ open</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Goto, Tadahiro</au><au>Morita, Sachiko</au><au>Kitamura, Tetsuhisa</au><au>Natsukawa, Tomoaki</au><au>Sawano, Hirotaka</au><au>Hayashi, Yasuyuki</au><au>Kai, Tatsuro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impact of extracorporeal cardiopulmonary resuscitation on outcomes of elderly patients who had out-of-hospital cardiac arrests: a single-centre retrospective analysis</atitle><jtitle>BMJ open</jtitle><addtitle>BMJ Open</addtitle><date>2018-05-18</date><risdate>2018</risdate><volume>8</volume><issue>5</issue><spage>e019811</spage><epage>e019811</epage><pages>e019811-e019811</pages><issn>2044-6055</issn><eissn>2044-6055</eissn><abstract>ObjectivesLittle is known about the effectiveness of extracorporeal cardiopulmonary resuscitation (ECPR) for elderly patients who had out-of-hospital cardiac arrest (OHCA). The aim of this study was to examine the impact of age on outcomes among patients who had OHCA treated with ECPR.DesignSingle-centre retrospective cohort study.SettingA critical care centre that covers a population of approximately 1 million residents.ParticipantsPatients who had consecutive OHCA aged ≥18 years who underwent ECPR from 2005 to 2013.Primary and secondary outcome measuresPrimary outcomes were 1 month neurologically favourable outcomes and survival. To determine the association between advanced age and each outcome, we fitted multivariable logistic regression models using: (1) age as a continuous variable and (2) age as a categorical variable (<50 years, 50–59 years, 60–69 years and ≥70 years).ResultsOverall, 144 patients who had OHCA who underwent ECPR were eligible for our analyses. The proportion of neurologically favourable outcomes was 7%, while survival was 19% in patients who had OHCA. After the adjustment for potential confounders, while advanced age was non-significantly associated with neurologically favourable outcomes (adjusted OR 0.96 (95% CI 0.91 to 1.01), p=0.08), the association between advanced age and the poor survival rate was significant (adjusted OR 0.96 (95% CI 0.93 to 0.99), p=0.04). Additionally, compared with age <50 years, age ≥70 years was non-significantly associated with poor neurological outcomes (adjusted OR 0.08 (95% CI 0.01 to 1.00), p=0.051), whereas age ≥70 years was significantly associated with worse survival in the adjusted model (adjusted OR 0.14 (95% CI 0.03 to 0.80), p=0.03).ConclusionsIn our analysis of consecutive OHCA data from a critical care hospital in an urban area of Japan, we found that advanced age was associated with the lower rate of 1-month survival in patients who had OHCA who underwent ECPR. Although larger studies are required to confirm these results, our findings suggest that ECPR may not be beneficial for patients who had OHCA aged ≥70 years.</abstract><cop>England</cop><pub>BMJ Publishing Group LTD</pub><pmid>29978808</pmid><doi>10.1136/bmjopen-2017-019811</doi><orcidid>https://orcid.org/0000-0002-5880-2968</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2044-6055 |
| ispartof | BMJ open, 2018-05, Vol.8 (5), p.e019811-e019811 |
| issn | 2044-6055 2044-6055 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5961566 |
| source | BMJ Open Access Journals; MEDLINE; DOAJ Directory of Open Access Journals; PubMed Central Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Age Age Factors Aged Ambulance services Cardiac arrest Cardiac arrhythmia Cardiopulmonary resuscitation Cardiopulmonary Resuscitation - mortality Chronic obstructive pulmonary disease Clinical Decision-Making CPR Critical care Emergency Medicine Extracorporeal membrane oxygenation Extracorporeal Membrane Oxygenation - mortality Female Heart attacks Hospitals Humans Japan Logistic Models Male Medical prognosis Medical records Middle Aged Older people Out-of-Hospital Cardiac Arrest - mortality Out-of-Hospital Cardiac Arrest - therapy Patients Physicians Retrospective Studies Systematic review |
| title | Impact of extracorporeal cardiopulmonary resuscitation on outcomes of elderly patients who had out-of-hospital cardiac arrests: a single-centre retrospective analysis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T14%3A39%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Impact%20of%20extracorporeal%20cardiopulmonary%20resuscitation%20on%20outcomes%20of%20elderly%20patients%20who%20had%20out-of-hospital%20cardiac%20arrests:%20a%20single-centre%20retrospective%20analysis&rft.jtitle=BMJ%20open&rft.au=Goto,%20Tadahiro&rft.date=2018-05-18&rft.volume=8&rft.issue=5&rft.spage=e019811&rft.epage=e019811&rft.pages=e019811-e019811&rft.issn=2044-6055&rft.eissn=2044-6055&rft_id=info:doi/10.1136/bmjopen-2017-019811&rft_dat=%3Cproquest_pubme%3E2099496447%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2099496447&rft_id=info:pmid/29978808&rfr_iscdi=true |