Challenges in nourishing the intrauterine growth-restricted foetus - Lessons learned from studies in the intrauterine growth-restricted foetal sheep

Previous attempts to improve growth and development of the intrauterine growth‐restricted (IUGR) foetus during pregnancy have not worked or caused harm. Our research identifies tissue‐specific mechanisms underlying foetal growth restriction and then tests strategies to improve growth and ameliorate...

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Veröffentlicht in:	Acta Paediatrica 2016-08, Vol.105 (8), p.881-889
Hauptverfasser:	Hay Jr, William W., Brown, Laura D., Rozance, Paul J., Wesolowski, Stephanie R., Limesand, Sean W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Animals Blood Transfusion Erythrocytes - chemistry Female Fetal Growth Retardation - therapy Glucose Glucose - biosynthesis Insulin Insulin - metabolism Insulin Secretion Intrauterine growth restriction Liver - metabolism Metabolism Models, Animal Muscle, Skeletal - embryology Oxygen Oxygen - blood Pancreas - metabolism Placental Insufficiency - physiopathology Pregnancy Prenatal development Sheep
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