Sensitive, High-Throughput, and Robust Trapping-Micro-LC-MS Strategy for the Quantification of Biomarkers and Antibody Biotherapeutics

For LC-MS-based targeted quantification of biotherapeutics and biomarkers in clinical and pharmaceutical environments, high sensitivity, high throughput, and excellent robustness are all essential but remain challenging. For example, though nano-LC-MS has been employed to enhance analytical sensitiv...

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Veröffentlicht in:Analytical chemistry (Washington) 2018-02, Vol.90 (3), p.1870-1880
Hauptverfasser: Zhang, Ming, An, Bo, Qu, Yang, Shen, Shichen, Fu, Wei, Chen, Yuan-Ju, Wang, Xue, Young, Rebeccah, Canty, John M, Balthasar, Joseph P, Murphy, Keeley, Bhattacharyya, Debadeep, Josephs, Jonathan, Ferrari, Luca, Zhou, Shaolian, Bansal, Surendra, Vazvaei, Faye, Qu, Jun
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Sprache:eng
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