Melanopsin-mediated pupil function is impaired in Parkinson’s disease

Parkinson’s disease (PD) is characterised by non-motor symptoms including sleep and circadian disruption. Melanopsin-expressing intrinsically photosensitive Retinal Ganglion Cells (ipRGC) transmit light signals to brain areas controlling circadian rhythms and the pupil light reflex. To determine if...

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Veröffentlicht in:	Scientific reports 2018-05, Vol.8 (1), p.7796-9, Article 7796
Hauptverfasser:	Joyce, Daniel S., Feigl, Beatrix, Kerr, Graham, Roeder, Luisa, Zele, Andrew J.
Format:	Artikel
Sprache:	eng
Schlagworte:	692/53/2421 692/699/375/1718 Aged Arousal Circadian Rhythm Circadian rhythms Female Humanities and Social Sciences Humans Male Melanopsin Middle Aged Movement disorders multidisciplinary Neurodegenerative diseases Parkinson Disease - physiopathology Parkinson's disease Photic Stimulation Reflex, Pupillary Retina Retinal ganglion cells Rod Opsins - physiology Science Science (multidisciplinary) Sleep
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