Deciphering the role of substrate stiffness to enhance internalization efficiency of plasmid DNA in stem cells using lipid-based nanocarriers

This study investigates the role of substrate stiffness on non-viral transfection of human adipose-derived stem cells (hASCs) with the aim to maximize hASCs expression of vascular endothelial growth factor (VEGF). The results confirm the direct effect of substrate stiffness in regulating cytoskeleta...

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Veröffentlicht in:Nanoscale 2018-05, Vol.10 (19), p.8947-8952
Hauptverfasser: Modaresi, Saman, Pacelli, Settimio, Whitlow, Jonathan, Paul, Arghya
Format: Artikel
Sprache:eng
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