PCB exposure and potential future cancer incidence in Slovak children: an assessment from molecular finger printing by Ingenuity Pathway Analysis (IPA®) derived from experimental and epidemiological investigations

The risk of cancer due to PCB exposure in humans is highly debated. In eastern Slovakia, high exposure of the population to organochlorines (especially PCBs) was associated with various disease and disorder pathways, viz., endocrine disruption , metabolic disorder & diabetes , and cancer , there...

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Veröffentlicht in:	Environmental science and pollution research international 2018-06, Vol.25 (17), p.16493-16507
Hauptverfasser:	Ghosh, Somiranjan, Loffredo, Christopher A., Mitra, Partha S., Trnovec, Tomas, Palkovicova Murinova, Lubica, Sovcikova, Eva, Hoffman, Eric P., Makambi, Kepher H., Dutta, Sisir K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Apoptosis Aquatic Pollution Atmospheric Protection/Air Quality Control/Air Pollution Biomarkers Blood cells Breast cancer breast neoplasms Child Children Chronic Disease - epidemiology chronic diseases Cohort Studies diabetes Diabetes mellitus Disease DNA microarrays Earth and Environmental Science Ecotoxicology Endocrine disruptors Environment Environmental Chemistry Environmental Health Environmental Pollutants - blood Environmental Pollutants - metabolism Environmental Pollutants - toxicity Environmental science epidemiological studies Epidemiology Exposure Fingerprinting Gene Expression Genes Health risks Humans Incidence Metabolic disorders Myc protein Neoplasms - chemically induced Oncostatin M Organochlorine compounds Ovarian cancer ovarian neoplasms p53 Protein PCB PCBs Risk Evaluation and Environmental Protection Polychlorinated biphenyls Polychlorinated Biphenyls - blood Polychlorinated Biphenyls - metabolism Polychlorinated Biphenyls - toxicity Printing Prostate cancer prostatic neoplasms Protein biosynthesis Protein synthesis quantitative polymerase chain reaction reverse transcriptase polymerase chain reaction risk Signal Transduction Signaling Slovakia stress response Waste Water Technology Water Management Water Pollution Control
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