Structural and Biomechanical Adaptations to Free-Fall Landing in Hindlimb Cortical Bone of Growing Female Rats
The purpose of the study was to investigate the adaptation process of hindlimb cortical bone subjected to free-fall landing training. Female Wistar rats (7 weeks old) were randomly assigned to four landing (L) groups and four age-matched control (C) groups (n = 12 per group): L1, L2, L4 L8, C1, C2,...
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| description | The purpose of the study was to investigate the adaptation process of hindlimb cortical bone subjected to free-fall landing training. Female Wistar rats (7 weeks old) were randomly assigned to four landing (L) groups and four age-matched control (C) groups (n = 12 per group): L1, L2, L4 L8, C1, C2, C4 and C8. Animals in the L1, L2, L4 and L8 groups were respectively subjected to 1, 2, 4 and 8 weeks of free-fall-landing training (40 cm height, 30 times/day and 5 days/week) while the C1, C2, C4 and C8 groups served as age-matched control groups. The tibiae of the L8 group were higher in cortical bone mineral content (BMC) than those in the C8 group (p < 0.05). Except for the higher bone mineralization over bone surface ratio (MS/BS, %) shown in the tibiae of the L1 group (p < 0.05), dynamic histomorphometry in the tibial and femoral cortical bone showed no difference between landing groups and their age-matched control groups. In the femora, the L1 group was lower than the C1 group in cortical bone area (Ct.Ar) and cortical thickness (Ct.Th) (p < 0.05); however, the L4 group was higher than the C4 group in Ct.Ar and Ct.Th (p |
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), Ct.Ar and Ct.Th was significantly higher in the L8 group than in the C8 group (p < 0.05). In biomechanical testing, fracture load (FL) of femora was lower in the L1 group than in the C1 group (p < 0.05). Conversely, yield load (YL), FL and yield load energy (YE) of femora, as well as FL of tibiae were all significantly higher in the L8 group than in the C8 group (p < 0.05). Free-fall landing training may initially compromise bone material. However, over time, the current free-fall landing training induced improvements in biomechanical properties and/or the structure of growing bones.]]></description><identifier>ISSN: 1303-2968</identifier><identifier>EISSN: 1303-2968</identifier><identifier>PMID: 29769819</identifier><language>eng</language><publisher>Turkey: Journal of Sports Science and Medicine</publisher><subject>Adaptation ; Adaptation (Physiology) ; Adaptation, Physiological ; Allostatic load ; Animals ; Biomechanical Phenomena ; Biomechanics ; Bone Density ; Bone Development ; Bones ; College professors ; Compact bone ; Computer simulation ; Cortical Bone - physiology ; Design ; Employment ; Exercise ; Extremities, Lower ; Female ; Femur ; Fourier transforms ; Health aspects ; Hindlimb ; Leg ; Metabolism ; Physical Conditioning, Animal ; Physical fitness ; Physiological adaptation ; Physiological aspects ; Physiological research ; Physiology ; Random Allocation ; Rats, Wistar ; Rodents ; Studies ; Tibia</subject><ispartof>Journal of sports science & medicine, 2018-06, Vol.17 (2), p.188-196</ispartof><rights>COPYRIGHT 2018 Journal of Sports Science and Medicine</rights><rights>COPYRIGHT 2018 Journal of Sports Science and Medicine</rights><rights>2018. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Journal of Sports Science and Medicine 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950735/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950735/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29769819$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lin, Hsin-Shih</creatorcontrib><creatorcontrib>Wang, Ho-Seng</creatorcontrib><creatorcontrib>Chiu, Hung-Ta</creatorcontrib><creatorcontrib>Cheng, Kuang-You B</creatorcontrib><creatorcontrib>Hsu, Ar-Tyan</creatorcontrib><creatorcontrib>Huang, Tsang-Hai</creatorcontrib><title>Structural and Biomechanical Adaptations to Free-Fall Landing in Hindlimb Cortical Bone of Growing Female Rats</title><title>Journal of sports science & medicine</title><addtitle>J Sports Sci Med</addtitle><description><![CDATA[The purpose of the study was to investigate the adaptation process of hindlimb cortical bone subjected to free-fall landing training. Female Wistar rats (7 weeks old) were randomly assigned to four landing (L) groups and four age-matched control (C) groups (n = 12 per group): L1, L2, L4 L8, C1, C2, C4 and C8. Animals in the L1, L2, L4 and L8 groups were respectively subjected to 1, 2, 4 and 8 weeks of free-fall-landing training (40 cm height, 30 times/day and 5 days/week) while the C1, C2, C4 and C8 groups served as age-matched control groups. The tibiae of the L8 group were higher in cortical bone mineral content (BMC) than those in the C8 group (p < 0.05). Except for the higher bone mineralization over bone surface ratio (MS/BS, %) shown in the tibiae of the L1 group (p < 0.05), dynamic histomorphometry in the tibial and femoral cortical bone showed no difference between landing groups and their age-matched control groups. In the femora, the L1 group was lower than the C1 group in cortical bone area (Ct.Ar) and cortical thickness (Ct.Th) (p < 0.05); however, the L4 group was higher than the C4 group in Ct.Ar and Ct.Th (p <0 .05). In the tibiae, the moment of inertia about the antero-posterior axis (
), Ct.Ar and Ct.Th was significantly higher in the L8 group than in the C8 group (p < 0.05). In biomechanical testing, fracture load (FL) of femora was lower in the L1 group than in the C1 group (p < 0.05). Conversely, yield load (YL), FL and yield load energy (YE) of femora, as well as FL of tibiae were all significantly higher in the L8 group than in the C8 group (p < 0.05). Free-fall landing training may initially compromise bone material. However, over time, the current free-fall landing training induced improvements in biomechanical properties and/or the structure of growing bones.]]></description><subject>Adaptation</subject><subject>Adaptation (Physiology)</subject><subject>Adaptation, Physiological</subject><subject>Allostatic load</subject><subject>Animals</subject><subject>Biomechanical Phenomena</subject><subject>Biomechanics</subject><subject>Bone Density</subject><subject>Bone Development</subject><subject>Bones</subject><subject>College professors</subject><subject>Compact bone</subject><subject>Computer simulation</subject><subject>Cortical Bone - physiology</subject><subject>Design</subject><subject>Employment</subject><subject>Exercise</subject><subject>Extremities, Lower</subject><subject>Female</subject><subject>Femur</subject><subject>Fourier transforms</subject><subject>Health aspects</subject><subject>Hindlimb</subject><subject>Leg</subject><subject>Metabolism</subject><subject>Physical Conditioning, Animal</subject><subject>Physical fitness</subject><subject>Physiological adaptation</subject><subject>Physiological aspects</subject><subject>Physiological research</subject><subject>Physiology</subject><subject>Random Allocation</subject><subject>Rats, Wistar</subject><subject>Rodents</subject><subject>Studies</subject><subject>Tibia</subject><issn>1303-2968</issn><issn>1303-2968</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNklFrFDEQxxdRbK1-BQkIog8rm2Rzm7wI18O7Fg4LVp9DNjvZS8km5yZb7bdvWqveSh8kDwmT3_yH_8w8KY4xrWhJxII_PXgfFS9ivKoqwhjhz4sjIpqF4FgcF_4yjZNO06gcUr5DpzYMoHfKW50jy07tk0o2-IhSQOsRoFwr59A2s9b3yHp0Zn3n7NCiVRjTfdZp8ICCQZsx_LiD1jAoB-iLSvFl8cwoF-HVw31SfFt_-ro6K7cXm_PVclv2teCp5JiwRhvKat6CWAijO9IqjqHijW451UopXOFOYA3GACMdaEUwVk1lTEMpPSk-_tLdT-0AnQafskO5H-2gxhsZlJXzH293sg_XkglWNZRlgXcPAmP4PkFMcrBRg3PKQ5iiJFVdNQtKeZPRN_-gV2EafbYnCREsG6pr8pfqcy-k9SbkuvpOVC5ZzWqKeYMz9eERKp8OBqtzX43N8VnC-1lCZhL8TL2aYpTnl5__m-Wb7ZwtH2N1cA56kHlYq4s5__aA34FyaReDm-53Zw6-PpzMn5H8Xkl6C03h2hU</recordid><startdate>20180601</startdate><enddate>20180601</enddate><creator>Lin, Hsin-Shih</creator><creator>Wang, Ho-Seng</creator><creator>Chiu, Hung-Ta</creator><creator>Cheng, Kuang-You B</creator><creator>Hsu, Ar-Tyan</creator><creator>Huang, Tsang-Hai</creator><general>Journal of Sports Science and Medicine</general><general>Uludag University</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>8GL</scope><scope>ISN</scope><scope>3V.</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88I</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M2P</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20180601</creationdate><title>Structural and Biomechanical Adaptations to Free-Fall Landing in Hindlimb Cortical Bone of Growing Female Rats</title><author>Lin, Hsin-Shih ; Wang, Ho-Seng ; Chiu, Hung-Ta ; Cheng, Kuang-You B ; Hsu, Ar-Tyan ; Huang, Tsang-Hai</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g498t-81257cf3548be969fcd2ba81e087cb83caaa101d91ceffe52deca211a70ff7333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adaptation</topic><topic>Adaptation (Physiology)</topic><topic>Adaptation, Physiological</topic><topic>Allostatic load</topic><topic>Animals</topic><topic>Biomechanical Phenomena</topic><topic>Biomechanics</topic><topic>Bone Density</topic><topic>Bone Development</topic><topic>Bones</topic><topic>College professors</topic><topic>Compact bone</topic><topic>Computer simulation</topic><topic>Cortical Bone - physiology</topic><topic>Design</topic><topic>Employment</topic><topic>Exercise</topic><topic>Extremities, Lower</topic><topic>Female</topic><topic>Femur</topic><topic>Fourier transforms</topic><topic>Health aspects</topic><topic>Hindlimb</topic><topic>Leg</topic><topic>Metabolism</topic><topic>Physical Conditioning, Animal</topic><topic>Physical fitness</topic><topic>Physiological adaptation</topic><topic>Physiological aspects</topic><topic>Physiological research</topic><topic>Physiology</topic><topic>Random Allocation</topic><topic>Rats, Wistar</topic><topic>Rodents</topic><topic>Studies</topic><topic>Tibia</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lin, Hsin-Shih</creatorcontrib><creatorcontrib>Wang, Ho-Seng</creatorcontrib><creatorcontrib>Chiu, Hung-Ta</creatorcontrib><creatorcontrib>Cheng, Kuang-You B</creatorcontrib><creatorcontrib>Hsu, Ar-Tyan</creatorcontrib><creatorcontrib>Huang, Tsang-Hai</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Gale In Context: High School</collection><collection>Gale In Context: Canada</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Science Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of sports science & medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lin, Hsin-Shih</au><au>Wang, Ho-Seng</au><au>Chiu, Hung-Ta</au><au>Cheng, Kuang-You B</au><au>Hsu, Ar-Tyan</au><au>Huang, Tsang-Hai</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Structural and Biomechanical Adaptations to Free-Fall Landing in Hindlimb Cortical Bone of Growing Female Rats</atitle><jtitle>Journal of sports science & medicine</jtitle><addtitle>J Sports Sci Med</addtitle><date>2018-06-01</date><risdate>2018</risdate><volume>17</volume><issue>2</issue><spage>188</spage><epage>196</epage><pages>188-196</pages><issn>1303-2968</issn><eissn>1303-2968</eissn><abstract><![CDATA[The purpose of the study was to investigate the adaptation process of hindlimb cortical bone subjected to free-fall landing training. Female Wistar rats (7 weeks old) were randomly assigned to four landing (L) groups and four age-matched control (C) groups (n = 12 per group): L1, L2, L4 L8, C1, C2, C4 and C8. Animals in the L1, L2, L4 and L8 groups were respectively subjected to 1, 2, 4 and 8 weeks of free-fall-landing training (40 cm height, 30 times/day and 5 days/week) while the C1, C2, C4 and C8 groups served as age-matched control groups. The tibiae of the L8 group were higher in cortical bone mineral content (BMC) than those in the C8 group (p < 0.05). Except for the higher bone mineralization over bone surface ratio (MS/BS, %) shown in the tibiae of the L1 group (p < 0.05), dynamic histomorphometry in the tibial and femoral cortical bone showed no difference between landing groups and their age-matched control groups. In the femora, the L1 group was lower than the C1 group in cortical bone area (Ct.Ar) and cortical thickness (Ct.Th) (p < 0.05); however, the L4 group was higher than the C4 group in Ct.Ar and Ct.Th (p <0 .05). In the tibiae, the moment of inertia about the antero-posterior axis (
), Ct.Ar and Ct.Th was significantly higher in the L8 group than in the C8 group (p < 0.05). In biomechanical testing, fracture load (FL) of femora was lower in the L1 group than in the C1 group (p < 0.05). Conversely, yield load (YL), FL and yield load energy (YE) of femora, as well as FL of tibiae were all significantly higher in the L8 group than in the C8 group (p < 0.05). Free-fall landing training may initially compromise bone material. However, over time, the current free-fall landing training induced improvements in biomechanical properties and/or the structure of growing bones.]]></abstract><cop>Turkey</cop><pub>Journal of Sports Science and Medicine</pub><pmid>29769819</pmid><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adaptation Adaptation (Physiology) Adaptation, Physiological Allostatic load Animals Biomechanical Phenomena Biomechanics Bone Density Bone Development Bones College professors Compact bone Computer simulation Cortical Bone - physiology Design Employment Exercise Extremities, Lower Female Femur Fourier transforms Health aspects Hindlimb Leg Metabolism Physical Conditioning, Animal Physical fitness Physiological adaptation Physiological aspects Physiological research Physiology Random Allocation Rats, Wistar Rodents Studies Tibia |
| title | Structural and Biomechanical Adaptations to Free-Fall Landing in Hindlimb Cortical Bone of Growing Female Rats |
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