Effects of peritumoral bevacizumab injection against oral squamous cell carcinoma in a nude mouse xenograft model: A preliminary study

Angiogenesis serves a crucial role in tumor growth. Vascular endothelial growth factor (VEGF) is a potent regulator of tumor angiogenesis and is highly expressed in oral squamous cell carcinoma (OSCC). Bevacizumab, which binds to VEGF-A, inhibits the biological activity of VEGF and is clinically adm...

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Veröffentlicht in:	Oncology letters 2018-06, Vol.15 (6), p.8627-8634
Hauptverfasser:	Yoshida, Hisato, Yoshimura, Hitoshi, Matsuda, Shinpei, Ryoke, Takashi, Kiyoshima, Tamotsu, Kobayashi, Motohiro, Sano, Kazuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Bevacizumab Biological activity Cancer therapies Chemotherapy Development and progression Drug therapy Health aspects Immunotherapy Lung cancer Medical prognosis Monoclonal antibodies Mouth cancer Oral cancer Patient outcomes Squamous cell carcinoma Targeted cancer therapy Tumors Vascular endothelial growth factor
Online-Zugang:	Volltext
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