The double-edged sword: Neurotoxicity of chemotherapy

Abstract The number of available therapies for hematologic malignancies continues to grow at a rapid pace. Unfortunately, many of these treatments carry both central and peripheral nervous system toxicities, potentially limiting a patient's ability to tolerate a full course of treatment. Neurot...

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Veröffentlicht in:	Blood reviews 2015-03, Vol.29 (2), p.93-100
Hauptverfasser:	Magge, Rajiv S, DeAngelis, Lisa M
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Inhibitors - adverse effects Angiogenesis Inhibitors - toxicity Animals Antibodies, Bispecific - adverse effects Antibodies, Bispecific - toxicity Antineoplastic Agents - adverse effects Antineoplastic Agents - toxicity Brain Diseases - chemically induced Brain Diseases - diagnosis Brain Diseases - etiology Chemotherapy Delirium Encephalopathy Hematologic Neoplasms - complications Hematologic Neoplasms - drug therapy Hematologic Neoplasms - therapy Hematology, Oncology and Palliative Medicine Hematopoietic Stem Cell Transplantation - adverse effects Humans Immunoconjugates - adverse effects Immunoconjugates - toxicity Immunotherapy - adverse effects Neuropathy Neurotoxicity Syndromes - diagnosis Neurotoxicity Syndromes - etiology Organoplatinum Compounds - adverse effects Organoplatinum Compounds - toxicity Rituximab - adverse effects Rituximab - toxicity Seizure Seizures - chemically induced Seizures - diagnosis Seizures - etiology Toxicity Vinca Alkaloids - adverse effects Vinca Alkaloids - toxicity
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