Targeted genomic landscape of metastases compared to primary tumours in clear cell metastatic renal cell carcinoma

Background The genomic landscape of primary clear cell renal cell carcinoma (ccRCC) has been well described. However, little is known about cohort genomic alterations (GA) landscape in ccRCC metastases, or how it compares to primary tumours in aggregate. The genomic landscape of metastases may have...

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Veröffentlicht in:	British journal of cancer 2018-05, Vol.118 (9), p.1238-1242
Hauptverfasser:	de Velasco, Guillermo, Wankowicz, Stephanie A., Madison, Russell, Ali, Siraj M., Norton, Craig, Duquette, Audrey, Ross, Jeffrey S., Bossé, Dominick, Lalani, Aly-Khan A., Miller, Vincent A., Stephens, Philip J., Young, Lauren, Hakimi, A. Ari, Signoretti, Sabina, Pal, Sumanta K., Choueiri, Toni K.
Format:	Artikel
Sprache:	eng
Schlagworte:	692/4028/67 692/4028/67/589/1588 Biomedical and Life Sciences Biomedicine Cancer Research Clear cell-type renal cell carcinoma Drug Resistance Epidemiology Kidney cancer Metastases Metastasis Molecular Medicine Mutation Oncology p53 Protein Tumors VHL protein
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