Structural insights into the molecular mechanism of mouse TRPA1 activation and inhibition

Pain, though serving the beneficial function of provoking a response to dangerous situations, is an unpleasant sensory and emotional experience. Transient receptor potential ankyrin 1 (TRPA1) is a member of the transient receptor potential (TRP) cation channel family and is localized in "nocice...

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Veröffentlicht in:The Journal of general physiology 2018-05, Vol.150 (5), p.751-762
Hauptverfasser: Samanta, Amrita, Kiselar, Janna, Pumroy, Ruth A, Han, Seungil, Moiseenkova-Bell, Vera Y
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Sprache:eng
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