Assembly and Purification of Prototype Foamy Virus Intasomes

A defining feature and necessary step of the retrovirus life cycle is the integration of the viral genome into the host genome. All retroviruses encode an integrase (IN) enzyme that catalyzes the covalent joining of viral to host DNA, which is known as strand transfer. Integration may be modeled in...

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Veröffentlicht in:	Journal of Visualized Experiments 2018-03 (133)
Hauptverfasser:	Mackler, Randi M., Lopez, Miguel A., Yoder, Kristine E.
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA, Viral - genetics Immunology and Infection Integrases - isolation & purification Spumavirus - chemistry
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