Endothelin Receptor A Antagonism and Fetal Growth in Endothelial Nitric Oxide Synthase Gene Knockout Maternal and Fetal Mice

Fetal growth restriction (FGR) is commonly associated with perinatal morbidity and mortality. Nitric oxide (NO) deficiency increases endothelin-1 (ET-1) production, and this increased ET-1 may contribute to the pathophysiology of NO deficiency-induced FGR. Using an endothelial NO synthase knockout m...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Reproductive sciences (Thousand Oaks, Calif.) Calif.), 2016-08, Vol.23 (8), p.1028-1036
Hauptverfasser:	Luo, Kehuan, Thaete, Larry G., Neerhof, Mark G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Embryology Endothelin A Receptor Antagonists - administration & dosage Endothelin-1 - metabolism Female Fetal Development - drug effects Fetal Growth Retardation - metabolism Fetal Weight - drug effects Maternal-Fetal Exchange Medicine & Public Health Mice Mice, Knockout Nitric Oxide Synthase Type III - deficiency Nitric Oxide Synthase Type III - genetics Obstetrics/Perinatology/Midwifery Original Original Article Placenta - drug effects Placenta - physiology Pregnancy Pyrrolidines - administration & dosage Receptor, Endothelin A - metabolism Reproductive Medicine RNA, Messenger - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!