In Vivo PET Assay of Tumor Glutamine Flux and Metabolism: In-Human Trial of 18F-(2S,4R)-4-Fluoroglutamine

Purpose To assess the clinical safety, pharmacokinetics, and tumor imaging characteristics of fluorine 18-(2S,4R)-4-fluoroglutamine (FGln), a glutamine analog radiologic imaging agent. Materials and Methods This study was approved by the institutional review board and conducted under a U.S. Food and...

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Veröffentlicht in:	Radiology 2018-05, Vol.287 (2), p.667-675
Hauptverfasser:	Dunphy, Mark P S, Harding, James J, Venneti, Sriram, Zhang, Hanwen, Burnazi, Eva M, Bromberg, Jacqueline, Omuro, Antonio M, Hsieh, James J, Mellinghoff, Ingo K, Staton, Kevin, Pressl, Christina, Beattie, Bradley J, Zanzonico, Pat B, Gerecitano, John F, Kelsen, David P, Weber, Wolfgang, Lyashchenko, Serge K, Kung, Hank F, Lewis, Jason S
Format:	Artikel
Sprache:	eng
Schlagworte:	Original Research
Online-Zugang:	Volltext
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